SCHEMBL7706083

SCHEMBL7706083

CC(C)(C)CC1CCNC1=O

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 5/20 0.34
PLG P00747 1/20 0.32
AR P10275 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7706087 1.00 CCR2 (0.34) CCR2PLGAR
SCHEMBL24963541 0.88 CCR2 (0.39) CCR2
SCHEMBL24188796 0.86 CCR2 (0.45) CCR2
SCHEMBL24189428 0.82 CCR2 (0.38) CCR2AR
SCHEMBL25766118 0.82 CCR2 (0.38) CCR2AR
SCHEMBL21164841 0.80 PLG (0.35) CCR2PLGAR
SCHEMBL25766120 0.80 CCR2 (0.40) CCR2AR
SCHEMBL12070429 0.80 CCR2 (0.33) CCR2AR
SCHEMBL12070430 0.80 CCR2 (0.33) CCR2AR
SCHEMBL30497365 0.79 AR (0.34) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018126-A1 ANTI-VIRAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2024-01-18 US disclosed
US-20240018126-A1 ANTI-VIRAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2024-01-18 US disclosed
US-20230212116-A1 SARS-COV-2 MAIN PROTEASE INHIBITORS THE TEXAS A&M UNIVERSITY SYSTEM 2023-07-06 US disclosed
US-20230212116-A1 SARS-COV-2 MAIN PROTEASE INHIBITORS THE TEXAS A&M UNIVERSITY SYSTEM 2023-07-06 US disclosed
US-20230140238-A1 ANTI-VIRAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-05-04 US disclosed
US-20230033285-A1 Protease Inhibitors for Treatment of Coronavirus Infections THE SCRIPPS RESEARCH INSTITUTE 2023-02-02 US disclosed
US-20220009903-A1 ANTI-VIRAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2022-01-13 US disclosed
US-11213525-B2 Linear glycosidase inhibitors ASCENEURON SA (CH) 2022-01-04 US disclosed
US-20210186958-A1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2021-06-24 US disclosed
US-11034692-B1 Naphthyridines as inhibitors of HPK1 GENENTECH, INC. (US) 2021-06-15 US disclosed
US-10392422-B2 Macrocyclic broad spectrum antibiotics RQX PHARMACEUTICALS, INC. (US) 2019-08-27 US disclosed
US-10351595-B2 2019-07-16 US disclosed
US-9790228-B2 Heterocyclic kinase inhibitors INTELLIKINE LLC (US) 2017-10-17 US disclosed
US-20170088582-A1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS RQX PHARMACEUTICALS, INC. (US) 2017-03-30 US disclosed
US-9169240-B2 Ketone linked benzothiazole inhibitors of endothelial lipase BRISTOL-MYERS SQUIBB COMPANY (US) 2015-10-27 US disclosed
US-20150239879-A1 KETONE LINKED BENZOTHIAZOLE INHIBITORS OF ENDOTHELIAL LIPASE BRISTOL-MYERS SQUIBB COMPANY 2015-08-27 US disclosed
US-7462594-B2 Peptide-like compounds that inhibit coronaviral 3CL and flaviviridae viral proteases TAIGEN BIOTECHNOLOGY CO., LTD. (TW) 2008-12-09 US disclosed
US-20050143320-A1 Protease inhibitors TAIGEN BIOTECHNOLOGY 2005-06-30 US disclosed
US-6610730-B2 Viricides; protease inbhibitor AGOURON PHARMACEUTICALS, INC. 2003-08-26 US disclosed
US-6534530-B1 Administering (benzo)thiazole peptidomimetic as viricide; protease inhibitors AGOURON PHARMACEUTICALS, INC. 2003-03-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11213525-B2 Linear glycosidase inhibitors ENGASE, GAA, GLA CCR2 4830/4885PLG 1052/4885AR 3427/4885
US-10351595-B2 MRPL21, PRSS1, PEPD CCR2 4440/4885PLG 297/4885AR 3751/4885
US-20210186958-A1 GLYCOSIDASE INHIBITORS ENGASE, GAA, GLA CCR2 4855/4885PLG 1443/4885AR 3103/4885
US-10392422-B2 Macrocyclic broad spectrum antibiotics MRPL21, PEPD, CTSC CCR2 4502/4885PLG 429/4885AR 2887/4885
US-20230140238-A1 ANTI-VIRAL COMPOUNDS EIF2AK2, ZC3HAV1, HAVCR2 CCR2 1926/4885PLG 4503/4885AR 4034/4885
US-20230212116-A1 SARS-COV-2 MAIN PROTEASE INHIBITORS ACE2, ACE, TMPRSS2 CCR2 1612/4885PLG 78/4885AR 2613/4885
US-20050143320-A1 Protease inhibitors PREP, SPINT2, SERPINB1 CCR2 3602/4885PLG 156/4885AR 2682/4885
US-20220009903-A1 ANTI-VIRAL COMPOUNDS EIF2AK2, ZC3HAV1, HAVCR2 CCR2 1926/4885PLG 4503/4885AR 4034/4885
US-11034692-B1 Naphthyridines as inhibitors of HPK1 NEK1, NEK5, NEK11 CCR2 4244/4885PLG 3839/4885AR 4848/4885
US-20240018126-A1 ANTI-VIRAL COMPOUNDS EIF2AK2, ZC3HAV1, HAVCR2 CCR2 1926/4885PLG 4503/4885AR 4034/4885
US-20230033285-A1 Protease Inhibitors for Treatment of Coronavirus Infections ACE, ACE2, TMPRSS2 CCR2 998/4885PLG 83/4885AR 1669/4885
US-20170088582-A1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS MRPL21, PEPD, CTSC CCR2 4502/4885PLG 429/4885AR 2887/4885
US-20150239879-A1 KETONE LINKED BENZOTHIAZOLE INHIBITORS OF ENDOTHELIAL LIPASE LIPG, LPL, LIPE CCR2 3212/4885PLG 292/4885AR 4208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.