Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1635426 | 0.87 | ACHE (0.50) | ACHECYP3A4MAPTPOLBGFER | |
| SCHEMBL29793476 | 0.87 | ACHE (0.50) | ACHECYP3A4MAPTPOLBGFER | |
| SCHEMBL10584398 | 0.85 | ACHE (0.48) | ACHECYP3A4MAPTPOLBGFER | |
| Iodide SCHEMBL8935417 | 0.85 | ACHE (0.48) | ACHECYP3A4MAPTPOLBGFER | |
| Iodobenzene SCHEMBL28037264 | 0.83 | ABCB1 (0.40) | ACHECYP3A4MAPTPOLBGFER | |
| Bromide SCHEMBL8935512 | 0.83 | ACHE (0.46) | ACHECYP3A4MAPTPOLBGFER | |
| Bromide SCHEMBL8935516 | 0.83 | ACHE (0.46) | ACHECYP3A4MAPTPOLBGFER | |
| SCHEMBL1243920 | 0.82 | ACHE (0.56) | ACHECYP3A4MAPTCA9PTGS2 | |
| SCHEMBL3674233 | 0.82 | ACHE (0.56) | ACHECYP3A4MAPTCA9PTGS2 | |
| SCHEMBL30835564 | 0.82 | ACHE (0.56) | ACHECYP3A4MAPTCA9PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355826-B1 | HALOMETHYLATION AN AROMATIC ALDEHYDE COMPOUND AND SALT FORMATION | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-03-12 | — | — | US | claimed |
| EP-0903338-A2 | Synthesis of stable nitrile oxide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-03-24 | — | — | EP | claimed |
| EP-2911656-B1 | QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS FOR OPHTHALMIC USE | NICOX SA (FR) | 2020-12-02 | — | — | EP | disclosed |
| US-9446015-B2 | Quinone based nitric oxide donating compounds for ophthalmic use | NICOX SCIENCE IRELAND (IE) | 2016-09-20 | — | — | US | disclosed |
| CN-104994845-A | Quinone based nitric oxide donating compounds for ophthalmic use | NICOX SA | 2015-10-21 | — | — | CN | disclosed |
| US-20150283106-A1 | QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS FOR OPHTHALMIC USE | NICOX SA (FR) | 2015-10-08 | — | — | US | disclosed |
| EP-2911656-A1 | QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS FOR OPHTHALMIC USE | Nicox Science Ireland (IE) | 2015-09-02 | — | — | EP | disclosed |
| US-9079821-B2 | Quinone based nitric oxide donating compounds | NICOX SCIENCE IRELAND (IE) | 2015-07-14 | — | — | US | disclosed |
| US-9061962-B2 | Quinone based nitric oxide donating compounds | NICOX SCIENCE IRELAND (IE) | 2015-06-23 | — | — | US | disclosed |
| EP-2707354-B1 | QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS | NICOX SCIENCE IRELAND (IE) | 2015-04-29 | — | — | EP | disclosed |
| US-20140342998-A1 | QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS | NICOX S.A. (FR) | 2014-11-20 | — | — | US | disclosed |
| WO-2014063923-A1 | QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS FOR OPHTHALMIC USE | NICOX S.A. (FR) | 2014-05-01 | — | — | WO | disclosed |
| EP-2722326-A1 | Quinone based nitric oxide donating compounds | NICOX S.A. (FR) | 2014-04-23 | — | — | EP | disclosed |
| EP-2707354-A1 | QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS | Nicox S.A. (FR) | 2014-03-19 | — | — | EP | disclosed |
| WO-2013060673-A1 | QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS | NICOX S.A. (FR) | 2013-05-02 | — | — | WO | disclosed |
| US-6355826-B1 | HALOMETHYLATION AN AROMATIC ALDEHYDE COMPOUND AND SALT FORMATION | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-03-12 | — | — | US | disclosed |
| EP-0903338-A2 | Synthesis of stable nitrile oxide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-03-24 | — | — | EP | disclosed |
| US-5319063-A | Crosslinking a phenolic compound, a trifunctional aromatic nucleus residue in presence of an | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-06-07 | — | — | US | disclosed |
| US-5216112-A | PHENOLIC RESIN AND METHOD FOR PREPARING SAME | MITSUI TOATSU CHEMICALS, INC. (JP) | 1993-06-01 | — | — | US | disclosed |
| EP-0475605-A2 | Phenolic resin and method for preparing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150283106-A1 | QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS FOR OPHTHALMIC USE | NOS1, NOS3, NOS2 | ACHE 1138/4885CYP3A4 759/4885MAPT 2671/4885 |
| US-20140342998-A1 | QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS | NOS2, NQO1, NOS1 | ACHE 719/4885CYP3A4 715/4885MAPT 2605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.