Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | NQO2 | P16083 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25952537 | 0.89 | ACHE (0.55) | ACHECYP3A4MAPTCA9PTGS2 | |
| SCHEMBL684130 | 0.86 | ACHE (0.59) | ACHECYP3A4MAPTCA9PTGS2 | |
| SCHEMBL3356035 | 0.83 | ACHE (0.62) | ACHECYP3A4MAPTCA9PTGS2 | |
| SCHEMBL16071623 | 0.83 | ACHE (0.52) | ACHECYP3A4MAPTCA9PTGS2 | |
| SCHEMBL679526 | 0.83 | ACHE (0.60) | ACHECYP3A4MAPTCA9PTGS2 | |
| SCHEMBL29287630 | 0.83 | ACHE (0.45) | ACHECYP3A4MAPTCA9PTGS2 | |
| SCHEMBL10603435 | 0.83 | HTR2A (0.49) | ACHECYP3A4MAPTCA9PTGS2 | |
| SCHEMBL7706095 | 0.82 | ACHE (0.48) | ACHECYP3A4MAPTCA9PTGS2 | |
| SCHEMBL12586888 | 0.82 | ACHE (0.54) | ACHECYP3A4MAPTCA9PTGS2 | |
| SCHEMBL28608445 | 0.80 | ACHE (0.42) | ACHECYP3A4MAPTCA9PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101973918-B | Synthesis method of coenzyme Q1 analogue | UNIV NORTHEAST FORESTRY | 2013-10-30 | — | — | CN | claimed |
| CN-101973918-A | Synthesis method of coenzyme Q1 analogue | UNIV NORTHEAST FORESTRY | 2011-02-16 | — | — | CN | claimed |
| US-20080200732-A1 | Novel Intermediates Useful for the Preparation of Coenzymes, Process for the Preparation of Novel Intermediates and an Improved Process for the Preparation of Coenzymes | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2008-08-21 | — | — | US | claimed |
| EP-1910263-A2 | NOVEL INTERMEDIATES USEFUL FOR THE PREPARATION OF COENZYMES, PROCESS FOR THE PREPARATION OF NOVEL INTERMEDIATES AND AN IMPROVED PROCESS FOR THE PREPARATION OF COENZYMES | Nicholas Piramal India Limited (IN) | 2008-04-16 | — | — | EP | claimed |
| WO-2007004091-A2 | NOVEL INTERMEDIATES USEFUL FOR THE PREPARATION OF COENZYMES, PROCESS FOR THE PREPARATION OF NOVEL INTERMEDIATES AND AN IMPROVED PROCESS FOR THE PREPARATION OF COENZYMES | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2007-01-11 | — | — | WO | claimed |
| EP-0243849-A2 | Process for the production of polyprenoid type compounds | YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED (IL) | 1987-11-04 | — | — | EP | claimed |
| US-20240400784-A1 | Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition | LG CHEM, LTD. (KR) | 2024-12-05 | — | — | US | disclosed |
| WO-2020025020-A1 | MEDICAL USE OF HYDROXY-SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS | 广东医科大学 | 2020-02-06 | — | — | WO | disclosed |
| CN-108904499-B | A kind of medical usage for the tetrahydro isoquinoline compound that hydroxyl replaces | 广东医科大学 | 2019-08-02 | — | — | CN | disclosed |
| CN-108904499-A | A kind of medical usage for the tetrahydro isoquinoline compound that hydroxyl replaces | 广东医科大学 | 2018-11-30 | — | — | CN | disclosed |
| EP-2203161-B1 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | UNIV INDIANA RES & TECH CORP (US) | 2018-05-09 | — | — | EP | disclosed |
| CN-103820506-B | A kind of method of gene recombination bacterium fermentation preparation of cozymase Q 10 | 湖南科源生物制品有限公司 | 2017-04-05 | — | — | CN | disclosed |
| US-9365513-B2 | Fullerene derivative, and method of preparing the same | RICOH COMPANY, LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| US-20080200732-A1 | Novel Intermediates Useful for the Preparation of Coenzymes, Process for the Preparation of Novel Intermediates and an Improved Process for the Preparation of Coenzymes | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2008-08-21 | — | — | US | disclosed |
| EP-1910263-A2 | NOVEL INTERMEDIATES USEFUL FOR THE PREPARATION OF COENZYMES, PROCESS FOR THE PREPARATION OF NOVEL INTERMEDIATES AND AN IMPROVED PROCESS FOR THE PREPARATION OF COENZYMES | Nicholas Piramal India Limited (IN) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007004091-A2 | NOVEL INTERMEDIATES USEFUL FOR THE PREPARATION OF COENZYMES, PROCESS FOR THE PREPARATION OF NOVEL INTERMEDIATES AND AN IMPROVED PROCESS FOR THE PREPARATION OF COENZYMES | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2007-01-11 | — | — | WO | disclosed |
| US-20040151711-A1 | Synthesis of coenzyme Q10, ubiquinone | WEST DANIEL DAVID (US) | 2004-08-05 | — | — | US | disclosed |
| US-6686485-B2 | FROM TOBACCO WASTES; THERAPY FOR BRAIN DISORDERS, PREVENT TISSUE DAMAGE | WEST DANIEL DAVID (US) | 2004-02-03 | — | — | US | disclosed |
| US-20020156302-A1 | Synthesis of coenzyme Q10, ubiquinone | WEST DANIEL DAVID (US) | 2002-10-24 | — | — | US | disclosed |
| EP-0243849-A2 | Process for the production of polyprenoid type compounds | YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED (IL) | 1987-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156302-A1 | Synthesis of coenzyme Q10, ubiquinone | SQLE, SQOR, NDUFA10 | ACHE 572/4885CYP3A4 416/4885MAPT 3178/4885 |
| US-20040151711-A1 | Synthesis of coenzyme Q10, ubiquinone | SQLE, SQOR, NDUFA10 | ACHE 572/4885CYP3A4 416/4885MAPT 3178/4885 |
| US-20080200732-A1 | Novel Intermediates Useful for the Preparation of Coenzymes, Process for the Preparation of Novel Intermediates and an Improved Process for the Preparation of Coenzymes | NDUFA10, NDUFA9, NDUFB10 | ACHE 1951/4885CYP3A4 340/4885MAPT 3285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.