Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706472 | 0.75 | GAA (0.67) | TSHRL3MBTL1TP53ALDH1A1LMNA | |
| SCHEMBL7819172 | 0.72 | TP53 (0.64) | TSHRL3MBTL1TP53ALDH1A1LMNA | |
| SCHEMBL20156432 | 0.71 | SMN1; SMN2 (0.46) | HTTGAA | |
| SCHEMBL7712463 | 0.71 | L3MBTL1 (0.70) | TSHRL3MBTL1TP53ALDH1A1LMNA | |
| SCHEMBL14132781 | 0.70 | LMNA (0.67) | TSHRL3MBTL1TP53ALDH1A1LMNA | |
| SCHEMBL12807968 | 0.69 | TP53 (0.78) | TSHRL3MBTL1TP53ALDH1A1LMNA | |
| SCHEMBL13325681 | 0.68 | RECQL (0.68) | TSHRTP53ALDH1A1LMNAAHR | |
| SCHEMBL29386004 | 0.68 | TP53 (0.74) | TSHRL3MBTL1TP53ALDH1A1LMNA | |
| SCHEMBL20539215 | 0.68 | LMNA (0.63) | TSHRL3MBTL1TP53ALDH1A1LMNA | |
| SCHEMBL14132985 | 0.67 | TP53 (0.74) | TSHRL3MBTL1TP53ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | claimed |
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | disclosed |