SCHEMBL770665

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15224201	0.86	HSD11B1 (0.47)	HSD11B1ITGB3ITGA2BCNR2F13A1
	SCHEMBL770396	0.84	HSD11B1 (0.46)	HSD11B1CNR2MBTD1L3MBTL3
	SCHEMBL770695	0.84	HSD11B1 (0.46)	HSD11B1ITGB3ITGA2BPOLB
	SCHEMBL771655	0.83	HSD11B1 (0.51)	HSD11B1CNR2MBTD1L3MBTL3ALDH1A1
	SCHEMBL770380	0.81	ITGB3 (0.48)	HSD11B1ITGB3ITGA2BPOLB
	SCHEMBL770767	0.81	ITGB3 (0.48)	HSD11B1ITGB3ITGA2BALDH1A1POLB
	SCHEMBL770302	0.81	PDE4B (0.47)	HSD11B1CNR2ALDH1A1POLB
	SCHEMBL770074	0.81	ALDH1A1 (0.50)	HSD11B1CNR2ALDH1A1POLB
	SCHEMBL770893	0.80	GNAI3 (0.46)	HSD11B1CNR2ALDH1A1
	SCHEMBL770400	0.80	GNAI3 (0.51)	HSD11B1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.