Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.57 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.51 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.46 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.46 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529939 | 0.78 | GSTP1 (0.47) | ALDH1A1KMT2AGSTP1SMN1; SMN2SCN4A | |
| SCHEMBL7703865 | 0.75 | GSTP1 (0.44) | KMT2AGSTP1SCN4A | |
| SCHEMBL8531642 | 0.74 | GSTP1 (0.43) | KMT2AGSTP1SMN1; SMN2 | |
| SCHEMBL8532142 | 0.74 | GSTP1 (0.43) | ALDH1A1GSTP1SMN1; SMN2SCN4A | |
| SCHEMBL8531965 | 0.74 | HSP90AA1 (0.50) | ALDH1A1SMN1; SMN2 | |
| Terephthalamide SCHEMBL4205368 | 0.74 | PARP10 (1.00) | PARP10PARP15PARP14TNKSTNKS2 | |
| SCHEMBL606429 | 0.74 | PARP10 (1.00) | PARP10PARP15PARP14TNKSTNKS2 | |
| SCHEMBL2531295 | 0.73 | PARP10 (0.83) | PARP10PARP15PARP14TNKSTNKS2 | |
| SCHEMBL30434552 | 0.73 | PARP10 (0.83) | PARP10PARP15PARP14TNKSTNKS2 | |
| SCHEMBL7703136 | 0.73 | LTA4H (0.46) | ALDH1A1KMT2AGSTP1SMN1; SMN2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216285-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | Ciba SC Holding AG (CH) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019939-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-03-22 | — | — | WO | disclosed |