Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.48 |
| ▸ | NPC1 | O15118 | 10/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7707115 | 0.90 | SMN1; SMN2 (0.46) | RAB9ASMN1; SMN2NPC1MAPTTP53 | |
| SCHEMBL7707516 | 0.88 | SMN1; SMN2 (0.46) | RAB9ASMN1; SMN2NPC1MAPTTP53 | |
| SCHEMBL7707191 | 0.85 | SMN1; SMN2 (0.50) | RAB9ASMN1; SMN2NPC1MAPTTP53 | |
| SCHEMBL7704577 | 0.83 | SMN1; SMN2 (0.48) | RAB9ASMN1; SMN2NPC1MAPTTP53 | |
| SCHEMBL6988611 | 0.79 | RAB9A (0.58) | RAB9ASMN1; SMN2NPC1MAPTTP53 | |
| SCHEMBL7092338 | 0.79 | EPHX2 (0.53) | RAB9ASMN1; SMN2NPC1MAPTTP53 | |
| SCHEMBL6989433 | 0.78 | ROCK2 (0.52) | RAB9ASMN1; SMN2NPC1MAPTTP53 | |
| SCHEMBL7139981 | 0.77 | MEN1 (0.56) | RAB9ASMN1; SMN2NPC1MAPTTP53 | |
| SCHEMBL7088422 | 0.77 | ALDH1A1 (0.51) | RAB9ASMN1; SMN2NPC1MAPTTP53 | |
| SCHEMBL7710313 | 0.76 | HDAC1 (0.54) | RAB9ASMN1; SMN2NPC1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6353007-B1 | ANTIINFLAMMATORY AGENTS AND INHIBITORS OF CELLULAR POLIFERATION | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-03-05 | — | — | US | claimed |
| US-6353007-B1 | ANTIINFLAMMATORY AGENTS AND INHIBITORS OF CELLULAR POLIFERATION | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-03-05 | — | — | US | disclosed |