Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 19/20 | 0.65 |
| ▸ | GABRA2 | P47869 | 18/20 | 0.65 |
| ▸ | GABRB2 | P47870 | 18/20 | 0.65 |
| ▸ | GABRP | O00591 | 15/20 | 0.65 |
| ▸ | GABRD | O14764 | 15/20 | 0.65 |
| ▸ | GABRA1 | P14867 | 15/20 | 0.65 |
| ▸ | GABRB1 | P18505 | 15/20 | 0.65 |
| ▸ | GABRG2 | P18507 | 15/20 | 0.65 |
| ▸ | GABRA5 | P31644 | 15/20 | 0.65 |
| ▸ | GABRA3 | P34903 | 15/20 | 0.65 |
| ▸ | GABRA4 | P48169 | 15/20 | 0.65 |
| ▸ | GABRE | P78334 | 15/20 | 0.65 |
| ▸ | GABRA6 | Q16445 | 15/20 | 0.65 |
| ▸ | GABRG1 | Q8N1C3 | 15/20 | 0.65 |
| ▸ | GABRG3 | Q99928 | 15/20 | 0.65 |
| ▸ | GABRQ | Q9UN88 | 15/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962955 | 0.87 | GABRB3 (0.65) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7711657 | 0.85 | GABRB3 (0.67) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7713221 | 0.84 | GABRB3 (0.65) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10562514 | 0.83 | GABRA2 (0.64) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL14996611 | 0.83 | GABRB3 (0.52) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6168749 | 0.83 | GABRB3 (0.68) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6054602 | 0.82 | GABRB3 (0.63) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6054612 | 0.82 | GABRB3 (0.59) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL12859479 | 0.80 | GABRB3 (0.50) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL239495 | 0.80 | GABRB3 (0.60) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372774-B1 | THESE COMPOUNDS POSSESS ARTHROPODICIDAL, PLANT NEMATOCIDAL, ANTHELMINTIC AND ANTI-PROTOZOAL PROPERTIES | RHONE-POULENC AGRICULTURE LTD. (GB) | 2002-04-16 | — | — | US | disclosed |
| EP-0967206-A1 | Derivatives of N-phenylpyrazoles | RHONE POULENC AGRICULTURE LTD. (GB) | 1999-12-29 | — | — | EP | disclosed |
| US-5916618-A | PESTICIDE FOR MEDICATED FEEDSTUFF, DIETARY CONCENTRATE OR SUPPLEMENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-06-29 | — | — | US | disclosed |
| US-5714191-A | PESTICIDES USED IN MEDICATED FEEDSTUFF, MINERAL SALT LICK OR EDIBLE BAIT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-02-03 | — | — | US | disclosed |
| US-5608077-A | INSECTICIDES, NEMATOCIDES, ANTHELMINTICS, ANTIPROTOZOA AGENTS | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-03-04 | — | — | US | disclosed |
| US-5547974-A | INSECTICIDES, NEMATOCIDES, ANTHELMINTICS | RHONE-POULENC AGRICULTURE LTD. (GB) | 1996-08-20 | — | — | US | disclosed |
| EP-0418016-B1 | N-phenylpyrazole derivatives as insecticides | RHONE POULENC AGRICULTURE (GB) | 1995-05-03 | — | — | EP | disclosed |
| CN-1027341-C | N-Phenylpyrazole Derivative Insecticides | MAY & BAKER LTD (FR) | 1995-01-11 | — | — | CN | disclosed |
| US-5232940-A | Controlling insects, plant nematodes, helminths, protozoa | BASF AGRO B.V., ARNHEM (NL), WADENSWIL-BRANCH (CH) | 1993-08-03 | — | — | US | disclosed |
| CN-1053233-A | N-phenylpyrazole derivatives as sterilant | RHONE POULENC AGRICULTURE (GB) | 1991-07-24 | — | — | CN | disclosed |
| EP-0418016-A1 | N-phenylpyrazole derivatives as insecticides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1991-03-20 | — | — | EP | disclosed |
| CN-88103601-A | N-PHENYLPYRAZOLE DERIVATIVES | — | 1988-12-28 | — | — | CN | disclosed |
| EP-0295118-A1 | N-phenylpyrazole derivatives | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1988-12-14 | — | — | EP | disclosed |
| EP-0295117-A1 | Derivatives of N-phenylpyrazoles | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1988-12-14 | — | — | EP | disclosed |