Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 4/20 | 0.37 |
| ▸ | EDNRA | P25101 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473906 | 0.82 | ALDH1A1 (0.43) | FABP4SLC22A12HPGDALDH1A1MAPK1 | |
| SCHEMBL7426960 | 0.81 | ALDH1A1 (0.51) | FABP4SLC22A12HPGDALDH1A1MAPK1 | |
| SCHEMBL7476678 | 0.74 | SLC22A12 (0.39) | FABP4SLC22A12HPGDALDH1A1EDNRB | |
| SCHEMBL7707715 | 0.72 | SLC22A12 (0.42) | SLC22A12ALDH1A1MAPK1EDNRBEDNRA | |
| SCHEMBL7424082 | 0.72 | SLC22A12 (0.42) | FABP4SLC22A12HPGDALDH1A1MAPK1 | |
| SCHEMBL7421878 | 0.72 | KDM4E (0.41) | FABP4SLC22A12HPGDALDH1A1MAPK1 | |
| SCHEMBL7474496 | 0.72 | MEN1 (0.43) | SLC22A12HPGDALDH1A1MAPK1EDNRA | |
| SCHEMBL7420612 | 0.70 | ALDH1A1 (0.44) | SLC22A12HPGDALDH1A1MAPK1EDNRA | |
| SCHEMBL7418839 | 0.69 | FABP4 (0.54) | FABP4SLC22A12ALDH1A1SMN1; SMN2PTPN11 | |
| SCHEMBL7422706 | 0.69 | SLC22A12 (0.41) | FABP4SLC22A12ALDH1A1MAPK1EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358992-B1 | Method of inhibiting neoplastic cells with indole derivatives | CELL PATHWAYS, INC. | 2002-03-19 | — | — | US | disclosed |