Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | B4GALT1 | P15291 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.32 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.32 |
| ▸ | GSTA2 | P09210 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
| ▸ | GSTM1 | P09488 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.31 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079078 | 0.90 | B4GALT1 (0.36) | B4GALT1P2RY12P2RY2STING1SLC28A1 | |
| SCHEMBL4078642 | 0.89 | B4GALT1 (0.34) | B4GALT1P2RY12P2RY2STING1 | |
| SCHEMBL4074795 | 0.84 | MEN1 (0.33) | B4GALT1P2RY12P2RY2MEN1KMT2A | |
| SCHEMBL7707747 | 0.77 | TDP1 (0.40) | TDP1P2RY12P2RY2MEN1KMT2A | |
| SCHEMBL7699861 | 0.65 | TK1 (0.45) | — | |
| SCHEMBL17198380 | 0.63 | TDP1 (0.45) | TDP1P2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL15678124 | 0.63 | SLC28A1 (0.44) | P2RY2STING1SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL30428170 | 0.62 | SLC28A1 (0.51) | TDP1P2RY12P2RY2SLC28A1SLC28A2 | |
| SCHEMBL17550556 | 0.62 | DUT (0.40) | TDP1P2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL17198593 | 0.61 | SLC28A1 (0.41) | TDP1P2RY2SLC28A1SLC28A2SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569686-B1 | Compounds and methods for synthesis of bicyclic nucleic acid analogs | ISIS PHARMACEUTICALS, INC. (US) | 2009-08-04 | — | — | US | disclosed |