SCHEMBL7708203

SCHEMBL7708203

CC(C)(C)c1cc[c]c(-c2ccc(Cl)cc2)c1-c1ccc(Cl)cc1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
IKBKB O14920 1/20 0.30
MAP3K14 Q99558 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7702892 0.84 TSHR (0.34)
SCHEMBL7708522 0.83 SENP1 (0.37)
SCHEMBL5891289 0.82 ALDH1A1 (0.32)
SCHEMBL8204676 0.80 ALDH1A1 (0.35) MEN1KMT2A
SCHEMBL7711403 0.80 PTGS2 (0.36)
SCHEMBL7711445 0.79 RIPK1 (0.31)
SCHEMBL7711577 0.77 MEN1 (0.30) MEN1KMT2A
SCHEMBL7708543 0.76 ALDH1A1 (0.33)
SCHEMBL14142280 0.74 CYP1A2 (0.34)
SCHEMBL8170202 0.74 TSHR (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed