SCHEMBL7708543

SCHEMBL7708543

CC(C)(C)c1cc[c]c(-c2ccc(Sc3ccccc3)cc2)c1-c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5891289 0.86 ALDH1A1 (0.32) ALDH1A1HPGD
SCHEMBL7708795 0.79 ALDH1A1 (0.30) ALDH1A1HPGD
SCHEMBL7702892 0.78 TSHR (0.34)
SCHEMBL7708325 0.77 ALDH1A1 (0.37) ALDH1A1HPGDMAOAMAOBSLC6A4
SCHEMBL7708522 0.76 SENP1 (0.37) ALDH1A1HPGDSLC6A4
SCHEMBL7708203 0.76 MEN1 (0.31)
SCHEMBL7711403 0.74 PTGS2 (0.36) ALDH1A1
SCHEMBL8204676 0.74 ALDH1A1 (0.35) ALDH1A1
SCHEMBL7711445 0.73 RIPK1 (0.31)
SCHEMBL14142280 0.71 CYP1A2 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed