Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20956274 | 0.79 | NAAA (0.47) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL649818 | 0.79 | MGAM (0.46) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL9571839 | 0.79 | MGAM (0.46) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL16411252 | 0.79 | MGAM (0.46) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL11434419 | 0.79 | MGAM (0.46) | MGAMGAASIMGAM2SMN1; SMN2 | |
| SCHEMBL3683181 | 0.79 | ALDH1A1 (0.44) | GAAKDM4EPKMALDH1A1TP53 | |
| SCHEMBL4682825 | 0.79 | ALDH1A1 (0.34) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL542103 | 0.79 | ADRA2A (0.43) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL2701579 | 0.78 | GAA (0.60) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL25178944 | 0.78 | GAA (0.44) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355713-B1 | THERMOPLASTIC RESINS ARE STABILIZED WITH B-ENAMINES OR DERIVATIVES OF ALCOHOLS,SUGARS, SUGAR ALCOHOLS, GLYCOSIDES AND OLIGOSACCHARIDES; DISCOLORATION INHIBITION | AKCROS, CHEMICALS (GB) | 2002-03-12 | — | — | US | disclosed |
| EP-0986605-A1 | BETA-KETOESTERS FOR USE AS POLYMER STABILISERS | AKCROS CHEMICALS (GB) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998054246-A1 | β-KETOESTERS FOR USE AS POLYMER STABILISERS | AKCROS CHEMICALS (GB) | 1998-12-03 | — | — | WO | disclosed |