Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 10/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | XPO1 | O14980 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708404 | 1.00 | NFE2L2 (0.46) | NFE2L2KDM4ELMNAGAAMAPT | |
| SCHEMBL7428144 | 1.00 | NFE2L2 (0.46) | NFE2L2KDM4ELMNAGAAMAPT | |
| SCHEMBL7428146 | 1.00 | NFE2L2 (0.46) | NFE2L2KDM4ELMNAGAAMAPT | |
| SCHEMBL30570847 | 0.76 | CTH (0.36) | KDM4EFDPSPLAUADRA2AADRA2B | |
| SCHEMBL33532490 | 0.76 | CCR1 (0.41) | KDM4EMAPTGRM5FDPSPLAU | |
| SCHEMBL74726 | 0.72 | NFE2L2 (0.50) | NFE2L2BACE1L3MBTL1PLAUADRA2A | |
| SCHEMBL74727 | 0.72 | NFE2L2 (0.50) | NFE2L2BACE1L3MBTL1PLAUADRA2A | |
| SCHEMBL74725 | 0.72 | NFE2L2 (0.50) | NFE2L2BACE1L3MBTL1PLAUADRA2A | |
| SCHEMBL25023811 | 0.72 | ALDH1A1 (0.35) | KDM4ELMNAGAAMAPTL3MBTL1 | |
| SCHEMBL7434812 | 0.72 | TUBB4A (0.50) | NFE2L2KDM4EMAPTTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |