SCHEMBL7708752

SCHEMBL7708752

CC(C)(C)C(=O)COc1ccccc1[S+](c1ccccc1OCC(=O)C(C)(C)C)c1ccccc1OCC(=O)C(C)(C)C.O=S(=O)([O-])C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
HTT P42858 1/20 0.45
AR P10275 1/20 0.35
VDR P11473 1/20 0.34
KMT2A Q03164 2/20 0.33
HSP90AA1 P07900 1/20 0.32
MMP1 P03956 5/20 0.32
MMP2 P08253 5/20 0.32
MMP9 P14780 5/20 0.32
MMP8 P22894 5/20 0.32
MMP13 P45452 5/20 0.32
HSD11B1 P28845 1/20 0.32
CA2 P00918 4/20 0.31
CA1 P00915 3/20 0.31
MAPK1 P28482 1/20 0.30
USP2 O75604 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7708732 0.84 ALDH1A1 (0.45) ALDH1A1HTTARVDRKMT2A
SCHEMBL7708593 0.82 ALDH1A1 (0.59) ALDH1A1HTTARVDRKMT2A
SCHEMBL29370267 0.81 ACLY (0.36) MMP1MMP2MMP9MMP8MMP13
SCHEMBL6662689 0.81 ACLY (0.36) MMP1MMP2MMP9MMP8MMP13
SCHEMBL8206336 0.81 ALDH1A1 (0.44) ALDH1A1HTTARVDRKMT2A
SCHEMBL2634848 0.77 HSD11B1 (0.39) MMP1MMP2MMP9MMP8MMP13
SCHEMBL30897218 0.77 HSD11B1 (0.39) MMP1MMP2MMP9MMP8MMP13
SCHEMBL31627575 0.76 CA2 (0.38) MMP1MMP2MMP9MMP8MMP13
SCHEMBL956713 0.76 CA2 (0.38) MMP1MMP2MMP9MMP8MMP13
SCHEMBL2634332 0.75 PTGDR2 (0.37) ALDH1A1KMT2ACA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed