Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL947675 | 0.89 | SRD5A1 (0.50) | CYP2A6MAOAMAOBL3MBTL1MEN1 | |
| SCHEMBL29935354 | 0.80 | HSD11B1 (0.54) | MAOAALDH1A1SRD5A1SRD5A2NPC1 | |
| SCHEMBL714287 | 0.80 | HSD11B1 (0.54) | MAOAALDH1A1SRD5A1SRD5A2NPC1 | |
| SCHEMBL7712676 | 0.80 | L3MBTL1 (0.51) | L3MBTL1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7712845 | 0.78 | RXRA (0.43) | ALDH1A1HPGDNOTUMKDM4E | |
| SCHEMBL14059227 | 0.78 | TDP1 (0.43) | L3MBTL1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14059339 | 0.78 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL7714581 | 0.73 | MAPT (0.40) | CYP2A6MAOAMAOBL3MBTL1MEN1 | |
| Propionic Acid SCHEMBL7672868 | 0.72 | MAOA (0.72) | CYP2A6MAOAMAOBL3MBTL1MEN1 | |
| Methyl Alcohol SCHEMBL11482048 | 0.72 | MAOA (0.88) | CYP2A6MAOAMAOBL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369110-B1 | PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM | SUMITOMO PHARMACEUTICALS COMPANY (JP) | 2002-04-09 | — | — | US | disclosed |
| EP-1083166-A1 | NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-14 | — | — | EP | disclosed |