SCHEMBL7709103

SCHEMBL7709103

NCCS(=O)(=O)c1[c]cccc1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA5A P35218 1/20 0.32
CA9 Q16790 1/20 0.32
LOXL2 Q9Y4K0 3/20 0.32
LOX P28300 1/20 0.31
HTR6 P50406 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3540671 0.81 PSIP1 (0.38) LOXL2HTR6
SCHEMBL3982652 0.81 CA2 (0.40) CA1CA2CA5ACA9LOX
SCHEMBL9771529 0.79 TSHR (0.30)
SCHEMBL6623865 0.78 PSIP1 (0.35)
SCHEMBL21491104 0.78 PSIP1 (0.32) CA1CA2CA5ACA9
SCHEMBL159759 0.78 PSIP1 (0.46) CA1CA2CA5ACA9
SCHEMBL3857912 0.77 MMP1 (0.36)
SCHEMBL6250297 0.77 APEX1 (0.49)
SCHEMBL11562313 0.76 HSD11B1 (0.32) CA1CA2CA5ACA9
SCHEMBL11487808 0.75 MMP1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311839-A Methylamine derivative is used for treating cancer as lysyl oxidase inhibitor 癌症研究协会皇家癌症医院 2019-02-05 CN disclosed
CN-1235979-C Cationic dye NIPPON CHEMICALS IND CO LTD (JP) 2006-01-11 CN disclosed
CN-1388183-A Cationic dye NIPPON CHEMICALS IND CO LTD (JP) 2003-01-01 CN disclosed
JP-2002348492-A NOVEL CATIONIC DYE NIPPON KAGAKU KOGYOSHO:KK 2002-12-04 JP disclosed