SCHEMBL7709554

SCHEMBL7709554

CC(=O)CC(=O)OC(C)Oc1ccc(-c2nc(-c3ccc(C)cc3C)nc(-c3ccc(C)cc3C)n2)c(O)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.34
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
NPC1 O15118 4/20 0.34
EGLN1 Q9GZT9 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
RAB9A P51151 2/20 0.33
ALPL P05186 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
FFAR1 O14842 1/20 0.32
ACACB O00763 2/20 0.32
ACACA Q13085 2/20 0.32
PPARG P37231 2/20 0.32
PPARA Q07869 2/20 0.32
CTSA P10619 2/20 0.32
KDM1A O60341 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7706817 0.84 PLK1 (0.33) MAPTNPC1EGLN1KMT2ARAB9A
SCHEMBL819248 0.82 NPC1 (0.35) MAPTALDH1A1GAANPC1EGLN1
SCHEMBL7125661 0.81 L3MBTL1 (0.38) MAPTALDH1A1GAANPC1EGLN1
SCHEMBL7117619 0.80 PLK1 (0.38) GAAEGLN1
SCHEMBL7122860 0.79 NPC1 (0.41) MAPTALDH1A1GAANPC1EGLN1
SCHEMBL25375164 0.78 ALDH2 (0.44) MAPTALDH1A1NPC1MEN1KMT2A
SCHEMBL27168219 0.78 TDP1 (0.51) MAPTALDH1A1GAANPC1MEN1
SCHEMBL25372450 0.78 SMN1; SMN2 (0.40) MAPTALDH1A1NPC1EGLN1MEN1
SCHEMBL7233158 0.77 LMNA (0.45) MAPTALDH1A1GAANPC1MEN1
SCHEMBL7709582 0.76 NPC1 (0.33) MAPTALDH1A1GAANPC1EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6355708-B2 USEFUL IN STABILIZING POLYMERS AND OTHER MATERIALS FROM DEGRADATION BY ENVIRONMENTAL FORCES SUCH AS ACTINIC RADIATION (ULTRAVIOLET LIGHT), OXIDATION, MOISTURE, ATMOSPHERIC POLLUTANTS CIBA SPECIALTY CHEMICALS CORPORATION 2002-03-12 US disclosed
US-20010031866-A1 Novel trisaryl-1,3,5-triazine ultraviolet light absorbers GUPTA RAM BABOO (US) 2001-10-18 US disclosed
US-6242597-B1 STABILIZERS WITH A BONDABLE GROUP HAVING AN ACTIVE (ACIDIC) HYDROGEN; MIGRATION BETWEEN POLYMER LAYERS IS REDUCED CIBA SPECIALTY CHEMICALS CORPORATION 2001-06-05 US disclosed
EP-1032563-A1 TRISARYL-1,3,5-TRIAZINE ULTRAVIOLET LIGHT ABSORBERS CYTEC TECHNOLOGY CORP. (US) 2000-09-06 EP disclosed
WO-1999026934-A1 TRISARYL-1,3,5-TRIAZINE ULTRAVIOLET LIGHT ABSORBERS CYTEC TECHNOLOGY CORP. (US) 1999-06-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031866-A1 Novel trisaryl-1,3,5-triazine ultraviolet light absorbers ERCC5, XRCC5, ERCC1 MAPT 178/4885ALDH1A1 71/4885GAA 968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.