Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11106287 | 0.74 | TERT (0.38) | KMT2ACYP3A4ALDH1A1LMNAHPGD | |
| SCHEMBL688159 | 0.73 | CYP3A4 (0.46) | POLBGSK3BMEN1KMT2AATR | |
| SCHEMBL13306791 | 0.72 | POLB (0.40) | POLBCYP3A4TSHRALOX15ALDH1A1 | |
| SCHEMBL1620461 | 0.71 | SMPD1 (0.39) | POLBMEN1KMT2ACYP3A4TSHR | |
| SCHEMBL1620646 | 0.71 | ALDH1A1 (0.41) | POLBKMT2ACYP3A4TSHRALOX15 | |
| SCHEMBL13085621 | 0.69 | POLB (0.37) | POLBCYP3A4TSHRALOX15ALDH1A1 | |
| SCHEMBL9231931 | 0.68 | POLB (0.36) | POLBMEN1KMT2ACYP3A4TSHR | |
| SCHEMBL6358713 | 0.66 | PLK1 (0.43) | POLBCYP3A4ALDH1A1LMNAHPGD | |
| SCHEMBL18332873 | 0.64 | PTGS2 (0.31) | MEN1KMT2ATSHRALDH1A1HPGD | |
| SCHEMBL76231 | 0.63 | ACHE (0.48) | MEN1KMT2ACYP3A4ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355634-B1 | OXIME DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-12 | — | — | US | claimed |