Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208168 | 0.80 | GPR35 (0.39) | GPR35ALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL457836 | 0.80 | TSHR (0.44) | ALDH1A1TDP1HSD17B10TSHRACHE | |
| SCHEMBL6676890 | 0.78 | GPR35 (0.52) | GPR35ALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL8922506 | 0.77 | CYP1A2 (0.39) | ALDH1A1TDP1HSD17B10TSHRACHE | |
| SCHEMBL455622 | 0.72 | ALDH1A1 (0.48) | ALDH1A1TDP1HSD17B10TSHRLMNA | |
| SCHEMBL5631987 | 0.72 | HSD17B10 (0.39) | ALDH1A1TDP1HSD17B10TSHRMEN1 | |
| SCHEMBL3047388 | 0.71 | GPR35 (0.46) | GPR35ALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL9651909 | 0.69 | TDP1 (0.36) | ALDH1A1TDP1HSD17B10TSHRMEN1 | |
| SCHEMBL7832200 | 0.69 | GPR35 (0.50) | GPR35ALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL27782172 | 0.69 | HSD17B10 (0.38) | ALDH1A1TDP1HSD17B10TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376548-B1 | FUNGICIDES; HERBICIDES; INSECTICIDES | ROHM AND HAAS COMPANY | 2002-04-23 | — | — | US | claimed |
| US-6376548-B1 | FUNGICIDES; HERBICIDES; INSECTICIDES | ROHM AND HAAS COMPANY | 2002-04-23 | — | — | US | disclosed |
| WO-2001056358-A2 | ENHANCED PROPERTIED PESTICIDES | ROHM AND HAAS COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |