Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 2/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11502537 | 0.81 | ALDH1A1 (0.46) | HSD17B10ALDH1A1MAPTTDP1CRHBP | |
| SCHEMBL9369721 | 0.80 | FASN (0.39) | ALDH1A1MAPTTDP1CRHBPCRHR2 | |
| SCHEMBL7380148 | 0.80 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2MAPTTDP1CRHBP | |
| SCHEMBL7822062 | 0.77 | ALDH1A1 (0.44) | HSD17B10ALDH1A1SMN1; SMN2RAB9ATDP1 | |
| SCHEMBL9493335 | 0.76 | HTT (0.38) | HSD17B10ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL6635967 | 0.75 | CYP1A2 (0.33) | ALDH1A1SMN1; SMN2MAPTTDP1MEN1 | |
| SCHEMBL457836 | 0.74 | TSHR (0.44) | HSD17B10ALDH1A1SMN1; SMN2MAPTTDP1 | |
| SCHEMBL7821293 | 0.73 | TDP1 (0.44) | HSD17B10ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL439377 | 0.72 | BRD4 (0.37) | HSD17B10ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL7709814 | 0.72 | GPR35 (0.38) | HSD17B10ALDH1A1SMN1; SMN2TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235670-B2 | Photogenerated reagents | Gao, Xiaolian | 2007-06-26 | — | — | US | disclosed |
| US-20060122408-A1 | Photogenerated reagents | LC SCIENCES LC | 2006-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122408-A1 | Photogenerated reagents | PPOX, PGR, GRHPR | HSD17B10 1059/4885ALDH1A1 1813/4885SMN1; SMN2 4876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.