Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.46 |
| ▸ | S100A4 | P26447 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208168 | 0.82 | GPR35 (0.39) | GPR35S100A4ALDH1A1TP53HPGD | |
| SCHEMBL18478 | 0.78 | TSHR (0.42) | GPR35ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL10731966 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TP53TSHRSMN1; SMN2TDP1 | |
| SCHEMBL301080 | 0.76 | TDP1 (0.34) | ALDH1A1TDP1CYP3A4HIF1A | |
| SCHEMBL9789548 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TP53HPGDTSHRMAPK1 | |
| SCHEMBL3042315 | 0.73 | GPR35 (0.42) | GPR35S100A4ALDH1A1TP53HPGD | |
| SCHEMBL4363348 | 0.73 | GPR35 (0.60) | GPR35S100A4ESR1ESR2MCL1 | |
| SCHEMBL6676890 | 0.72 | GPR35 (0.52) | GPR35ALDH1A1TP53HPGDTSHR | |
| SCHEMBL7646276 | 0.72 | ABCC8 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL7709814 | 0.71 | GPR35 (0.38) | GPR35S100A4ALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079757-B1 | PROCESS FOR SELECTIVELY LOCALIZING ACTIVE INGREDIENTS ON AND IN MITOCHONDRIA AND CORRESPONDING ACTIVE INGREDIENTS | UGICHEM GES FÜR ORGANISCHE CHEMIE MBH (AT) | 2014-12-17 | — | — | EP | claimed |
| US-8362243-B2 | Method for selective localization of active agents at and in mitochondria and corresponding active agents | UGICHEM GESELLSCHAFT FUER ORGANISCHE CHEMIE MBH (AT) | 2013-01-29 | — | — | US | claimed |
| US-20100009895-A1 | METHOD FOR SELECTIVE LOCALIZATION OF ACTIVE AGENTS AT AND IN MITOCHONDRIA AND CORRESPONDING ACTIVE AGENTS | UGICHEM GESELLSCHAFT FUER ORGANISCHE CHEMIE MBH (AT) | 2010-01-14 | — | — | US | claimed |
| CN-101547934-A | Process for selectively localizing active ingredients on and in mitochondria and corresponding active ingredients | UGICHEM GES FUER ORGANISCHE CH (AT) | 2009-09-30 | — | — | CN | claimed |
| JP-11106367-A | — | — | None | — | — | JP | disclosed |
| JP-5363327-B2 | — | — | 2013-12-11 | — | — | JP | disclosed |
| US-8362243-B2 | Method for selective localization of active agents at and in mitochondria and corresponding active agents | UGICHEM GESELLSCHAFT FUER ORGANISCHE CHEMIE MBH (AT) | 2013-01-29 | — | — | US | disclosed |
| US-8362243-B2 | Method for selective localization of active agents at and in mitochondria and corresponding active agents | UGICHEM GESELLSCHAFT FUER ORGANISCHE CHEMIE MBH (AT) | 2013-01-29 | — | — | US | disclosed |
| US-20100009895-A1 | METHOD FOR SELECTIVE LOCALIZATION OF ACTIVE AGENTS AT AND IN MITOCHONDRIA AND CORRESPONDING ACTIVE AGENTS | UGICHEM GESELLSCHAFT FUER ORGANISCHE CHEMIE MBH (AT) | 2010-01-14 | — | — | US | disclosed |
| US-20100009895-A1 | METHOD FOR SELECTIVE LOCALIZATION OF ACTIVE AGENTS AT AND IN MITOCHONDRIA AND CORRESPONDING ACTIVE AGENTS | UGICHEM GESELLSCHAFT FUER ORGANISCHE CHEMIE MBH (AT) | 2010-01-14 | — | — | US | disclosed |
| CN-101547934-A | Process for selectively localizing active ingredients on and in mitochondria and corresponding active ingredients | UGICHEM GES FUER ORGANISCHE CH (AT) | 2009-09-30 | — | — | CN | disclosed |
| CN-101547934-A | Process for selectively localizing active ingredients on and in mitochondria and corresponding active ingredients | UGICHEM GES FUER ORGANISCHE CH (AT) | 2009-09-30 | — | — | CN | disclosed |
| EP-2079757-A2 | PROCESS FOR SELECTIVELY LOCALIZING ACTIVE INGREDIENTS ON AND IN MITOCHONDRIA AND CORRESPONDING ACTIVE INGREDIENTS | Ugichem Gesellschaft Für Organische Chemie MbH (AT) | 2009-07-22 | — | — | EP | disclosed |
| EP-2079757-A2 | PROCESS FOR SELECTIVELY LOCALIZING ACTIVE INGREDIENTS ON AND IN MITOCHONDRIA AND CORRESPONDING ACTIVE INGREDIENTS | Ugichem Gesellschaft Für Organische Chemie MbH (AT) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008049583-A3 | PROCESS FOR SELECTIVELY LOCALIZING ACTIVE INGREDIENTS ON AND IN MITOCHONDRIA AND CORRESPONDING ACTIVE INGREDIENTS | UGICHEM GES FUER ORGANISCHE CH (AT) | 2009-04-16 | — | — | WO | disclosed |
| WO-2008049583-A2 | PROCESS FOR SELECTIVELY LOCALIZING ACTIVE INGREDIENTS ON AND IN MITOCHONDRIA AND CORRESPONDING ACTIVE INGREDIENTS | Ugichem Gesellschaft für Organische Chemie mbH (AT) | 2008-05-02 | — | — | WO | disclosed |
| WO-2008049583-A2 | PROCESS FOR SELECTIVELY LOCALIZING ACTIVE INGREDIENTS ON AND IN MITOCHONDRIA AND CORRESPONDING ACTIVE INGREDIENTS | Ugichem Gesellschaft für Organische Chemie mbH (AT) | 2008-05-02 | — | — | WO | disclosed |
| JP-H11106367-A | PRODUCTION OF BIS(3-AMINO-4-HYDROXYPHENYL) COMPOUNDS | NIPPON KAYAKU CO LTD | 1999-04-20 | — | — | JP | disclosed |
| EP-0201417-A1 | Surfactant composition, process for its preparation and its use | RHONE-POULENC CHIMIE (FR) | 1986-11-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009895-A1 | METHOD FOR SELECTIVE LOCALIZATION OF ACTIVE AGENTS AT AND IN MITOCHONDRIA AND CORRESPONDING ACTIVE AGENTS | TFB2M, TFAM, SHMT2 | GPR35 1586/4885S100A4 1671/4885ESR1 4457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.