Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7558272 | 0.88 | MAPT (0.38) | NPSR1MAPTPOLBKDM4EKMT2A | |
| SCHEMBL2209439 | 0.79 | NPSR1 (0.45) | NPSR1MAPTPOLBKDM4EKMT2A | |
| SCHEMBL2211499 | 0.78 | ALDH1A1 (0.41) | NPSR1MAPTPOLBKDM4EKMT2A | |
| SCHEMBL28344959 | 0.72 | NPSR1 (0.44) | NPSR1MAPTPOLBKDM4EKMT2A | |
| SCHEMBL14020795 | 0.72 | NPSR1 (0.52) | NPSR1MAPTPOLBKDM4EKMT2A | |
| SCHEMBL3459141 | 0.72 | NPSR1 (0.41) | NPSR1MAPTPOLBKDM4EKMT2A | |
| SCHEMBL9056100 | 0.72 | NPSR1 (0.49) | NPSR1MAPTPOLBKDM4EKMT2A | |
| SCHEMBL4846541 | 0.71 | SMN1; SMN2 (0.35) | NPSR1MAPTPOLBKDM4EKMT2A | |
| SCHEMBL4846388 | 0.71 | KDM4E (0.31) | NPSR1MAPTPOLBKDM4EKMT2A | |
| SCHEMBL4847287 | 0.71 | SMN1; SMN2 (0.33) | NPSR1MAPTPOLBKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489513-B2 | REACTING AROMATIC BROMINE COMPOUND WITH DIPHENYLPHOSPHINIC CHLORIDE IN A MIXTURE OF TETRAHYDROFURAN AND AROMATIC HYDROCARBON TO GIVE A DIPHENYLPHOSPHINE OXIDE, ISOLATING, METALATING; REACTING WITH IODINE, REACTING WITH COPPER | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-03 | — | — | US | disclosed |
| US-20020058814-A1 | Process for the preparation of enantiomerically pure (5,5'-dichloro-6,6'-dimethoxy-biphenyl-2,2'-diyl)- bis(diphenylphosphine oxides) | LANXESS DEUTSCHLAND GMBH (DE) | 2002-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058814-A1 | Process for the preparation of enantiomerically pure (5,5'-dichloro-6,6'-dimethoxy-biphenyl-2,2'-diyl)- bis(diphenylphosphine oxides) | DDT, HDHD5, DDC | NPSR1 3249/4885MAPT 1329/4885POLB 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.