SCHEMBL7712101

SCHEMBL7712101

O=C(O)c1ccc([N+](=O)[O-])c(CCO)c1

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 1/20 0.62
TSHR P16473 2/20 0.57
POLB P06746 1/20 0.56
LMNA P02545 1/20 0.53
HCAR3 P49019 13/20 0.49
APEX1 P27695 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8092214 0.89 CASP6 (0.64) CASP6TSHRLMNAHCAR3APEX1
SCHEMBL18027781 0.87 CASP6 (0.66) CASP6TSHRPOLBLMNAHCAR3
SCHEMBL17399916 0.86 CASP6 (0.60) CASP6TSHRPOLBLMNAHCAR3
SCHEMBL1609806 0.83 CASP6 (0.66) CASP6TSHRPOLBLMNAHCAR3
SCHEMBL10757957 0.83 HCAR3 (0.58) CASP6TSHRPOLBLMNAHCAR3
SCHEMBL15174048 0.82 CASP6 (0.64) CASP6TSHRPOLBLMNAHCAR3
SCHEMBL7643058 0.82 CASP6 (0.64) CASP6TSHRPOLBLMNAHCAR3
Hydrochloric Acid SCHEMBL1609389 0.82 CASP6 (0.64) CASP6TSHRPOLBLMNAHCAR3
SCHEMBL28640811 0.82 VCAM1 (0.53) LMNA
SCHEMBL30208600 0.82 VCAM1 (0.53) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112661691-B O-nitroacetophenol derivative and preparation method and application thereof 广东省科学院化工研究所 2023-02-28 CN disclosed
EP-1217435-A1 Silver halide photographic element and imaging process EASTMAN KODAK COMPANY (US) 2002-06-26 EP disclosed
US-6361931-B1 REACTIVITY, STABILITY EASTMAN KODAK COMPANY 2002-03-26 US disclosed