SCHEMBL7712232

SCHEMBL7712232

CC(C)=C(CCN)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.44
CYP19A1 P11511 7/20 0.41
CYP3A4 P08684 1/20 0.41
ESR1 P03372 9/20 0.40
ESR2 Q92731 6/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
NOS2 P35228 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11043479 0.84 PTGS2 (0.42) PTGS2CYP19A1CYP3A4ESR1ESR2
SCHEMBL5283226 0.84 PTGS2 (0.41) PTGS2CYP19A1CYP3A4ESR1ESR2
SCHEMBL9310232 0.82 ESR1 (0.58) PTGS2CYP19A1ESR1ESR2CES2
SCHEMBL12174192 0.80 LMNA (0.45) PTGS2CYP19A1ESR1ESR2CES2
SCHEMBL16697815 0.79 CES1 (0.42) PTGS2CYP3A4CES2CES1
SCHEMBL17523673 0.79 PTGS2 (0.61) PTGS2CYP19A1CYP3A4ESR1ESR2
SCHEMBL28364073 0.78 ALDH1A1 (0.55) PTGS2
SCHEMBL11125618 0.77 PTGS2 (0.63) PTGS2ESR1CES2CES1
SCHEMBL25455453 0.76 PTGS2 (0.42) PTGS2CYP19A1CYP3A4ESR1ESR2
SCHEMBL9310985 0.76 ESR1 (0.55) PTGS2CYP19A1CYP3A4ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101074515-B Telescopic nonwoven fabric KAO CORP 2011-02-09 CN claimed
CN-1652756-A Matrix type patch containing bronchodilators AHN GOOK PHARMACEUTICAL CO LTD (KR) 2005-08-10 CN claimed
EP-1147138-A1 HYDROPHILIC AMPHOLYTIC POLYMER The B.F. Goodrich Company (US) 2001-10-24 EP claimed
WO-2000039176-A1 HYDROPHILIC AMPHOLYTIC POLYMER THE B.F. GOODRICH COMPANY (US) 2000-07-06 WO claimed
CN-103210145-B For increasing composition and the method for the dry strength of paper product Camiro Head Office (FI) 2016-05-25 CN disclosed
CN-103210145-A Composition and process for increasing the dry strength of a paper product KEMIRA OYJ 2013-07-17 CN disclosed
CN-101557929-B Stretchable sheet and process for producing the stretchable sheet KAO CORP 2012-09-05 CN disclosed
CN-101074515-B Telescopic nonwoven fabric KAO CORP 2011-02-09 CN disclosed
CN-101778873-A High solids glyoxalated polyacrylamide BUCKMAN LABOR INC 2010-07-14 CN disclosed
CN-101622382-A Organic-inorganic electrospun fibers PPG IND OHIO INC 2010-01-06 CN disclosed
CN-101557929-A Stretchable sheet and process for producing the stretchable sheet KAO CORP (JP) 2009-10-14 CN disclosed
CN-100467020-C Matrix type patch containing bronchodilators AHN GOOK PHARMACEUTICAL CO LTD (KR) 2009-03-11 CN disclosed
CN-101074515-A Telescopic nonwoven fabric KAO CORP (JP) 2007-11-21 CN disclosed
CN-1253233-C Filter for blood treatment and method for producing the same ASAHI MEDICAL CO (JP) 2006-04-26 CN disclosed
CN-1652756-A Matrix type patch containing bronchodilators AHN GOOK PHARMACEUTICAL CO LTD (KR) 2005-08-10 CN disclosed
CN-1489485-A Filter for blood treatment and method for producing the same ��ҽѧ��ʽ���� 2004-04-14 CN disclosed
US-6361768-B1 POLYMER FORMED BY COPOLYMERIZATION OF ANIONIC MONOMER HAVING CARBOXY-FUNCTIONAL GROUP, NON-QUATERNIZED CATIONIC MONOMER HAVING AMINO-FUNCTIONAL GROUP, NON-IONIC HYDROPHILIC MONOMER, HYDROPHOBIC MONOMER, OPTIONAL CROSSLINKING MONOMER PMD HOLDINGS CORP. 2002-03-26 US disclosed
EP-1147138-A1 HYDROPHILIC AMPHOLYTIC POLYMER The B.F. Goodrich Company (US) 2001-10-24 EP disclosed
WO-2000039176-A1 HYDROPHILIC AMPHOLYTIC POLYMER THE B.F. GOODRICH COMPANY (US) 2000-07-06 WO disclosed