Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072928 | 1.00 | KDM4E (0.49) | KDM4EGAACYP2C19LMNAHSD17B10 | |
| Acetic Acid SCHEMBL27542077 | 0.97 | KDM4E (0.47) | KDM4EGAACYP2C19LMNAHSD17B10 | |
| Acetic Acid SCHEMBL27542062 | 0.97 | KDM4E (0.47) | KDM4EGAACYP2C19LMNAHSD17B10 | |
| Acetic Acid SCHEMBL27432920 | 0.97 | KDM4E (0.47) | KDM4EGAACYP2C19LMNAHSD17B10 | |
| SCHEMBL8076939 | 0.88 | LMNA (0.44) | KDM4EGAALMNAHSD17B10MAPT | |
| SCHEMBL8066959 | 0.85 | ALDH1A1 (0.43) | KDM4EGAACYP2C19LMNAMEN1 | |
| SCHEMBL25318352 | 0.85 | GAA (0.50) | KDM4EGAALMNAHSD17B10MEN1 | |
| SCHEMBL25246324 | 0.85 | CYP2C19 (0.50) | KDM4ECYP2C19LMNAMEN1KMT2A | |
| SCHEMBL8080089 | 0.84 | L3MBTL1 (0.43) | CYP2C19LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL27432922 | 0.83 | CYP2C19 (0.53) | KDM4EGAACYP2C19LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365398-B1 | REACTING RACEMIC CARBOXYLIC ACID ESTER WITH RACEMIC ALCOHOL IN PRESENCE OF A CARBOXYL ESTER HYDROLASE | BASF AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | disclosed |