SCHEMBL8066959

SCHEMBL8066959

C=COC(=O)C(CC)c1ccc(C)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
LMNA P02545 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GAA P10253 2/20 0.38
RECQL P46063 1/20 0.38
STAT3 P40763 1/20 0.36
POLB P06746 1/20 0.36
KDM4E B2RXH2 2/20 0.36
ACHE P22303 1/20 0.36
DHODH Q02127 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8080089 0.86 L3MBTL1 (0.43) ALDH1A1MEN1KMT2AL3MBTL1LMNA
SCHEMBL7713499 0.85 KDM4E (0.49) ALDH1A1MEN1KMT2AL3MBTL1LMNA
SCHEMBL7072928 0.85 KDM4E (0.49) ALDH1A1MEN1KMT2AL3MBTL1LMNA
Acetic Acid SCHEMBL27542062 0.83 KDM4E (0.47) MEN1KMT2AL3MBTL1LMNATDP1
Acetic Acid SCHEMBL27432920 0.83 KDM4E (0.47) MEN1KMT2AL3MBTL1LMNATDP1
Acetic Acid SCHEMBL27542077 0.83 KDM4E (0.47) MEN1KMT2AL3MBTL1LMNATDP1
SCHEMBL8074900 0.82 PTGS2 (0.49) LMNACYP2C9
SCHEMBL8076939 0.81 LMNA (0.44) ALDH1A1LMNASMN1; SMN2TDP1GAA
SCHEMBL1476384 0.80 L3MBTL1 (0.57) ALDH1A1MEN1KMT2AL3MBTL1LMNA
SCHEMBL28321416 0.78 ALDH1A1 (0.46) ALDH1A1MEN1KMT2AL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1031629-A2 Method of preparation of stereoisomeric carboxylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2000-08-30 EP disclosed