SCHEMBL8080089

SCHEMBL8080089

C=COC(=O)C(CC)c1ccc(Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.43
FFAR2 O15552 2/20 0.42
HTT P42858 2/20 0.41
MAPK1 P28482 1/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
POLB P06746 2/20 0.39
KCNQ2 O43526 1/20 0.39
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
BRD4 O60885 1/20 0.38
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
NOS2 P35228 1/20 0.36
CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8066959 0.86 ALDH1A1 (0.43) L3MBTL1MEN1KMT2ACYP2C9CYP2C19
SCHEMBL7713499 0.84 KDM4E (0.49) L3MBTL1HTTMAPTMEN1KMT2A
SCHEMBL7072928 0.84 KDM4E (0.49) L3MBTL1HTTMAPTMEN1KMT2A
Acetic Acid SCHEMBL27542077 0.81 KDM4E (0.47) L3MBTL1HTTMAPTMEN1KMT2A
Acetic Acid SCHEMBL27542062 0.81 KDM4E (0.47) L3MBTL1HTTMAPTMEN1KMT2A
Acetic Acid SCHEMBL27432920 0.81 KDM4E (0.47) L3MBTL1HTTMAPTMEN1KMT2A
SCHEMBL8074900 0.81 PTGS2 (0.49) CYP2C9LMNA
SCHEMBL27676916 0.80 L3MBTL1 (0.61) L3MBTL1FFAR2HTTMAPK1MAPT
SCHEMBL7629387 0.80 L3MBTL1 (0.61) L3MBTL1FFAR2HTTMAPK1MAPT
SCHEMBL4517176 0.80 L3MBTL1 (0.49) L3MBTL1FFAR2HTTMAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1031629-A2 Method of preparation of stereoisomeric carboxylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2000-08-30 EP disclosed