SCHEMBL284305

SCHEMBL284305

COc1cccc(N)c1C(=O)O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.74
CA1 P00915 1/20 0.74
CA2 P00918 1/20 0.74
CA7 P43166 1/20 0.74
CA9 Q16790 1/20 0.74
CA14 Q9ULX7 1/20 0.74
ALDH1A1 P00352 3/20 0.52
ADRA2B P18089 1/20 0.52
PTGS1 P23219 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
PPARA Q07869 1/20 0.50
FABP4 P15090 1/20 0.44
HTT P42858 1/20 0.44
TSHR P16473 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
KDM4E B2RXH2 1/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28701488 0.90 CA12 (0.61) CA12CA1CA2CA7CA9
2,6-Dimethoxybenzoic Acid SCHEMBL149926 0.86 CA12 (1.00) CA12CA1CA2CA7CA9
SCHEMBL2199440 0.85 CA9 (0.57) CA12CA1CA2CA7CA9
SCHEMBL349002 0.85 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL29788626 0.85 CA9 (0.57) CA12CA1CA2CA7CA9
SCHEMBL7713669 0.84 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL6753855 0.84 HTT (0.55) CA12CA1CA2CA7CA9
SCHEMBL4708761 0.84 CA12 (0.56) CA12CA1CA2CA7CA9
2,6-Dimethoxybenzoic Acid SCHEMBL7867072 0.84 CA12 (0.95) CA12CA1CA2CA7CA9
2,6-Dimethoxybenzoic Acid SCHEMBL11457745 0.84 CA12 (0.95) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 577 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10669274-B2 Azaphenalene-3-one derivative, preparation method therefor, and application therof SUZHOU KANGRUN PHARMACEUTICALS INC. (CN) 2020-06-02 US claimed
US-20200031828-A1 AZAPHENALENE-3-ONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEROF SUZHOU KANGRUN PHARMACEUTICALS INC. (CN) 2020-01-30 US claimed
CN-107488790-B With the method for the copolymer adsorbing separation palladium of aniline and 2- amino -6- methoxy benzoic acid, platinum, rhodium 云南大学 2019-04-12 CN claimed
CN-106883232-B A kind of derivative and the preparation method and application thereof of non-that alkene -3- ketone of azepine 苏州康润医药有限公司 2019-01-22 CN claimed
US-4673740-A Preparation of substituted 2-phenyl-4H-3,1-benzoxazin-4-ones BASF AKTIENGESELLSCHAFT (DE) 1987-06-16 US claimed
EP-3886904-B1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-22 EP disclosed
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME KULEON LLC (US) 2026-04-02 US disclosed
US-12559464-B2 Quinazolinone dione compounds and uses thereof EDGEWISE THERAPEUTICS, INC. (US) 2026-02-24 US disclosed
EP-4688756-A1 QUINAZOLINE DIONE COMPOUNDS AND USES THEREOF EDGEWISE THERAPEUTICS, INC. (US) 2026-02-11 EP disclosed
EP-4678641-A1 QUINOLINONE COMPOUND AND NAPHTHYRIDINONE COMPOUND AND USE THEREOF Shanghai Helioson Pharmaceutical Co., Ltd. (CN) 2026-01-14 EP disclosed
US-12486234-B2 PAPD5 inhibitors and methods of use thereof CHILDREN'S MEDICAL CENTER CORPORATION (US) 2025-12-02 US disclosed
US-20250340513-A1 NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS KULEON LLC (US) 2025-11-06 US disclosed
US-4154961-A Oxamic acid derivatives AMERICAN HOME PRODUCTS CORPORATION (US) 1979-05-15 US disclosed
US-4116981-A 5,12-EPOXY-NAPHTHACENE-6,11-DIONE DERIVATIVES Tsay, Yuh-Geng (TW) 1978-09-26 US disclosed
US-4069343-A OXAMIC ACID DERIVATIVES FOR THE PREVENTION OF IMMEDIATE TYPE HYPERSENSITIVITY REACTIONS AMERICAN HOME PRODUCTS CORPORATION (US) 1978-01-17 US disclosed
US-4054661-A Pyridyl oxamic acid derivatives and use in the prevention of allergic reactions AMERICAN HOME PRODUCTS CORPORATION (US) 1977-10-18 US disclosed
US-4054657-A Pyrimidinyl oxamic acids and esters, and compositions and methods for the suppression of allergic manifestations AMERICAN HOME PRODUCTS CORPORATION (US) 1977-10-18 US disclosed
US-4054666-A Compositions and methods of treating immediate hypersensitivity reactions with thiazolyl oxamic acid derivatives AMERICAN HOME PRODUCTS CORPORATION (US) 1977-10-18 US disclosed
US-4036837-A 2 Alkoxyoxamoyl-pyrazines AMERICAN HOME PRODUCTS CORPORATION (US) 1977-07-19 US disclosed
US-3966965-A Oxamic acid derivatives for the prevention of immediate type hypersensitivity reactions AMERICAN HOME PRODUCTS CORPORATION (US) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME HTR2C, HTR7, HTR6 CA12 2458/4885CA1 1158/4885CA2 2151/4885
US-12486234-B2 PAPD5 inhibitors and methods of use thereof POT1, PARP15, TERT CA12 4473/4885CA1 4386/4885CA2 4531/4885
US-20250340513-A1 NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS HTR2A, HTR2C, HTR3A CA12 4068/4885CA1 2256/4885CA2 3924/4885
US-20200031828-A1 AZAPHENALENE-3-ONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEROF PARP1, PARP11, PARP8 CA12 4722/4885CA1 4738/4885CA2 4645/4885
US-10669274-B2 Azaphenalene-3-one derivative, preparation method therefor, and application therof PARP1, PARP11, PARP8 CA12 4722/4885CA1 4738/4885CA2 4645/4885
US-12559464-B2 Quinazolinone dione compounds and uses thereof TNNI3, TNNT2, TNNC1 CA12 4671/4885CA1 3863/4885CA2 1838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.