Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18403739 | 0.64 | OXTR (0.32) | KDM4EPKM | |
| SCHEMBL5136349 | 0.63 | GAA (0.32) | KDM4EPKM | |
| SCHEMBL11034491 | 0.60 | KDM4E (0.36) | KDM4EPKM | |
| SCHEMBL5837474 | 0.60 | KDM4E (0.39) | KDM4EPKM | |
| SCHEMBL27390499 | 0.60 | KDM4E (0.46) | KDM4EPKM | |
| SCHEMBL31756888 | 0.59 | KDM4E (0.35) | KDM4EPKM | |
| SCHEMBL8429771 | 0.59 | KDM4E (0.35) | KDM4EPKM | |
| SCHEMBL6545109 | 0.59 | KDM4E (0.35) | KDM4EPKM | |
| SCHEMBL9666306 | 0.59 | KDM4E (0.38) | KDM4EPKM | |
| SCHEMBL13105950 | 0.58 | MAPT (0.33) | KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191142-B1 | Aroyl aminoacyl pyrroles for use in the treatment of neuropathic pain | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-02-20 | — | — | US | claimed |
| US-6369228-B2 | ANTICONVULSANTS | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-04-09 | — | — | US | disclosed |
| EP-1154996-A2 | AROYL AMINOACYL PYRROLES FOR USE IN THE TREATMENT OF NEUROPATHIC PAIN | Ortho-McNeil Pharmaceutical, Inc. (US) | 2001-11-21 | — | — | EP | disclosed |
| US-6191142-B1 | Aroyl aminoacyl pyrroles for use in the treatment of neuropathic pain | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-02-20 | — | — | US | disclosed |
| WO-2000048584-A2 | AROYL AMINOACYL PYRROLES FOR USE IN THE TREATMENT OF NEUROPATHIC PAIN | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2000-08-24 | — | — | WO | disclosed |