Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 3/20 | 0.43 |
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3785373 | 0.82 | HTR7 (0.61) | HTR7NPC1ALDH1A1ATMHSD17B10 | |
| SCHEMBL890771 | 0.81 | AR (0.49) | RXRARARBRARGRXRBRXRG | |
| Hydrochloric Acid SCHEMBL6620601 | 0.80 | AR (0.48) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL25390971 | 0.76 | TSHR (0.62) | RXRARARBRARGRXRBRXRG | |
| Aminobenzoic Acid SCHEMBL8639392 | 0.76 | NOS1 (0.48) | SRD5A2SMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL2120264 | 0.76 | HTR7 (0.46) | HTR7SMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL3789854 | 0.76 | HTR7 (0.46) | HTR7SMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL2040404 | 0.76 | FOLH1 (0.58) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL36017 | 0.74 | TSHR (0.59) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL31236746 | 0.74 | TSHR (0.59) | RXRARARBRARGRXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376515-B2 | DERIVATIVES OF A 2-((4-AMIDINYLPHENYL)-CARBONYLAMINO-1,2-PHENYLENE)-CARBONYLAMINO-) PYRIDINE; POTENT AND HIGHLY SELECTIVE ANTICOAGULANTS; BIOAVAILABILITY AND/OR SOLUBILITY; PREVENTION AND TREATMENT OF THROMBOSIS AND COAGULATION | COR THERAPEUTICS, INC. | 2002-04-23 | — | — | US | disclosed |