Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA5A | P35218 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515761 | 0.83 | AOC3 (0.54) | — | |
| SCHEMBL4768334 | 0.82 | KDM4E (0.53) | FFAR1CTSLCTSBCTSSHRH3 | |
| SCHEMBL4688780 | 0.78 | FFAR1 (0.60) | FFAR1CTSLCTSBCTSSHRH3 | |
| SCHEMBL6670619 | 0.76 | CTSL (0.43) | FFAR1CTSLCTSBCTSSHRH3 | |
| SCHEMBL20200086 | 0.76 | FFAR1 (0.54) | FFAR1CTSLCTSBCTSSHRH3 | |
| SCHEMBL4084155 | 0.75 | AGXT (0.48) | — | |
| SCHEMBL1058423 | 0.75 | CTBP2 (0.50) | ALDH1A1 | |
| SCHEMBL361027 | 0.74 | ALOX5 (0.53) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL7463211 | 0.74 | FFAR1 (0.50) | FFAR1CTSLCTSBCTSSHRH3 | |
| SCHEMBL1515860 | 0.74 | LMNA (0.43) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369077-B1 | OSTEOPOROSIS, PERIODONTITIS, AND ARTHRITIS | SMITHKLINE BEECHAM CORPORATION | 2002-04-09 | — | — | US | disclosed |