Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.46 |
| ▸ | RAD51 | Q06609 | 3/20 | 0.45 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719496 | 0.80 | KDM4E (0.59) | ALDH1A1KDM5BRAD51KDM4EHSD17B10 | |
| SCHEMBL7716577 | 0.77 | KDM4E (0.63) | ALDH1A1KDM5BRAD51KCNQ3KCNQ2 | |
| SCHEMBL4612369 | 0.74 | ABCC9 (0.66) | ALDH1A1KDM5BRAD51KCNQ3KCNQ2 | |
| SCHEMBL7711920 | 0.71 | SMN1; SMN2 (0.33) | ALDH1A1KDM5BRAD51KDM4EHSD17B10 | |
| SCHEMBL7715688 | 0.70 | KDM4E (0.35) | ALDH1A1KDM4EHSD17B10LMNAMEN1 | |
| SCHEMBL7711899 | 0.70 | KDM5B (0.46) | ALDH1A1KDM5BRAD51KCNQ3KCNQ2 | |
| SCHEMBL23414710 | 0.69 | ALDH1A1 (0.49) | ALDH1A1KDM5BPKMKDM4EL3MBTL1 | |
| SCHEMBL7716579 | 0.69 | LOXL2 (0.54) | ALDH1A1KDM5BRAD51KCNQ3KCNQ2 | |
| SCHEMBL7711788 | 0.69 | KDM4E (0.64) | ALDH1A1KCNQ3KCNQ2PKMKDM4E | |
| SCHEMBL26847224 | 0.65 | FABP4 (0.60) | ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6379395-B1 | DYEING FOR HAIR DYE | L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | claimed |
| EP-0888109-B1 | KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-PYRIMIDINEOXO COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHODS | OREAL (FR) | 2000-08-30 | — | — | EP | claimed |
| US-6379395-B1 | DYEING FOR HAIR DYE | L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | disclosed |
| US-6179882-B1 | OXIDATION COLOR DYES | L'OREAL (FR) | 2001-01-30 | — | — | US | disclosed |