Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | RAD51 | Q06609 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.45 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.45 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.45 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.45 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4612369 | 0.81 | ABCC9 (0.66) | KDM4ELMNARAD51ALDH1A1KDM5B | |
| SCHEMBL461294 | 0.78 | KDM4E (1.00) | KDM4ELMNARAD51TDP1HSD17B10 | |
| SCHEMBL7711899 | 0.77 | KDM5B (0.46) | KDM4ELMNARAD51ALDH1A1KDM5B | |
| SCHEMBL7715697 | 0.77 | ALDH1A1 (0.47) | KDM4ELMNARAD51HSD17B10ALDH1A1 | |
| SCHEMBL7711788 | 0.75 | KDM4E (0.64) | KDM4ELMNAHSD17B10ALDH1A1HPGD | |
| SCHEMBL7716579 | 0.72 | LOXL2 (0.54) | KDM4ERAD51ALDH1A1HPGDKDM5B | |
| SCHEMBL688253 | 0.69 | KDM4E (1.00) | KDM4ELMNATDP1HSD17B10ALDH1A1 | |
| SCHEMBL23415012 | 0.67 | ALDH1A1 (0.64) | KDM4ELMNAHSD17B10ALDH1A1RAB9A | |
| SCHEMBL23415014 | 0.67 | KDM4E (0.56) | KDM4ELMNATDP1HSD17B10ALDH1A1 | |
| SCHEMBL31449507 | 0.67 | ALPI (0.46) | KDM4EALDH1A1KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888109-B1 | KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-PYRIMIDINEOXO COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHODS | OREAL (FR) | 2000-08-30 | — | — | EP | claimed |
| US-6379395-B1 | DYEING FOR HAIR DYE | L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | disclosed |
| US-6179882-B1 | OXIDATION COLOR DYES | L'OREAL (FR) | 2001-01-30 | — | — | US | disclosed |