Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 6/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718527 | 0.82 | ITGB1 (0.64) | ITGB1ITGA4MEN1KMT2APOLB | |
| SCHEMBL7710825 | 0.81 | ITGB1 (0.65) | ITGB1ITGA4ALDH1A1MEN1NPC1 | |
| SCHEMBL7718665 | 0.77 | ITGB1 (0.52) | ITGB1ITGA4PPARGPPARAMME | |
| Hydrochloric Acid SCHEMBL8450022 | 0.73 | PDCD1 (0.46) | ALDH1A1KMT2APPARGPPARATAS1R3 | |
| SCHEMBL8771914 | 0.72 | KIF11 (0.46) | MEN1KMT2ASMN1; SMN2PTGS1MAPK1 | |
| SCHEMBL7714337 | 0.72 | SCN9A (0.55) | ALDH1A1PPARGPPARAACEALOX15 | |
| Hydrochloric Acid SCHEMBL7570098 | 0.71 | TPH1 (0.45) | MEN1KMT2ASMN1; SMN2MAPK1PPARG | |
| SCHEMBL7710690 | 0.70 | ATM (0.39) | ITGB1ITGA4MAPTPOLBPTGDR | |
| SCHEMBL7568664 | 0.69 | MME (0.49) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL7102711 | 0.68 | PPARG (0.53) | ITGB1ITGA4PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455539-B2 | AUTOIMMUNE DISEASE; ANTIINFLAMMATORY AGENTS; ANTIPROLIFERATORY AGENTS | CELLTECH R&D LIMITED (GB) | 2002-09-24 | — | — | US | disclosed |
| US-20010020017-A1 | Squaric acid derivatives | CELLTECH R&D LIMITED (GB) | 2001-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010020017-A1 | Squaric acid derivatives | SUCNR1, HCAR1, CCR1 | ITGB1 20/4885ITGA4 435/4885ALDH1A1 282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.