Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TK1 | P04183 | 1/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.40 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3490250 | 0.86 | KIF11 (0.49) | KIF11KMT2AMEN1KCNH2TK1 | |
| SCHEMBL19522241 | 0.86 | SLC6A1 (0.44) | KIF11KMT2AMEN1KCNH2TK1 | |
| SCHEMBL15281845 | 0.86 | KIF11 (0.49) | KIF11KMT2AMEN1KCNH2TK1 | |
| SCHEMBL10434091 | 0.85 | LMNA (0.46) | KIF11KMT2AMEN1KCNH2SLC6A1 | |
| SCHEMBL10434128 | 0.85 | LMNA (0.46) | KIF11KMT2AMEN1KCNH2SLC6A1 | |
| SCHEMBL24937040 | 0.85 | LMNA (0.46) | KIF11KMT2AMEN1KCNH2SLC6A1 | |
| SCHEMBL16472146 | 0.84 | KIF11 (0.50) | KIF11KMT2AMEN1KCNH2TK1 | |
| SCHEMBL27081312 | 0.84 | KIF11 (0.50) | KIF11KMT2AMEN1KCNH2TK1 | |
| SCHEMBL21431103 | 0.83 | TK1 (0.46) | KIF11KMT2AMEN1KCNH2TK1 | |
| SCHEMBL5140315 | 0.82 | KIF11 (0.40) | KIF11KMT2AMEN1KCNH2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739351-B1 | MONOMERIC DIOLS AND PHOSPHATE LINKED OLIGOMERS FORMED THEREFROM | ISIS PHARMACEUTICALS INC (US) | 2002-04-10 | — | — | EP | disclosed |
| US-5886177-A | ETHYLENE GLYCOL MONOMERS JOINED VIA STANDARD PHOSPHATE LINKAGES INCLUDING PHOSPHOROTHIOATE, PHOSPHODIESTER, AND PHOSPHORAMIDATE LINKAGES; USEFUL FUNCTIONAL GROUPS INCLUDE NUCLEOBASES AS WELL AS POLAR GROUPS, HYDROPHOBIC GROUPS | ISIS PHARMACEUTICALS, INC. (US) | 1999-03-23 | — | — | US | disclosed |
| EP-0739351-A4 | MONOMERIC DIOLS AND PHOSPHATE LINKED OLIGOMERS FORMED THEREFROM | ISIS PHARMACEUTICALS INC (US) | 1998-10-21 | — | — | EP | disclosed |
| EP-0739351-A1 | MONOMERIC DIOLS AND PHOSPHATE LINKED OLIGOMERS FORMED THEREFROM | ISIS PHARMACEUTICALS, INC. (US) | 1996-10-30 | — | — | EP | disclosed |
| WO-1995018820-A1 | MONOMERIC DIOLS AND PHOSPHATE LINKED OLIGOMERS FORMED THEREFROM | ISIS PHARMACEUTICALS, INC. (US) | 1995-07-13 | — | — | WO | disclosed |