Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.66 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | DNM2 | P50570 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11445700 | 0.81 | MAPT (0.50) | NUDT1MAPTHTR6ALDH1A1CYP3A4 | |
| SCHEMBL20109484 | 0.79 | NUDT1 (1.00) | NUDT1HTR6 | |
| SCHEMBL15360171 | 0.79 | NUDT1 (0.43) | NUDT1TAAR1DNM2MEN1KMT2A | |
| SCHEMBL12499637 | 0.73 | NOS3 (0.58) | NUDT1MAPTHTR6ALDH1A1CYP3A4 | |
| SCHEMBL8873701 | 0.72 | NUDT1 (0.38) | NUDT1TAAR1DNM2MEN1KMT2A | |
| SCHEMBL11037706 | 0.71 | HTR6 (0.47) | NUDT1MAPTHTR6ALDH1A1CYP3A4 | |
| SCHEMBL15360169 | 0.71 | LMNA (0.42) | NUDT1MAPTHTR6ALDH1A1CYP3A4 | |
| SCHEMBL7834630 | 0.71 | HTR6 (0.76) | MAPTHTR6ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL7825258 | 0.71 | HTR6 (0.60) | NUDT1MAPTHTR6ALDH1A1CYP3A4 | |
| SCHEMBL7804825 | 0.70 | NUDT1 (0.36) | NUDT1TAAR1DNM2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380263-B1 | ADMINISTERING TO HUMAN EFFECTIVE TYROSINASE ACTIVITY-STIMULATING AMOUNT OF AT LEAST ONE 6-SUBSTITUTED PYRIMIDINE 3-OXIDE COMPOUND FOR PROMOTING PIGMENTATION OF THE SKIN AND/OR HAIR | SOCIETE L'OREAL (FR) | 2002-04-30 | — | — | US | disclosed |