Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14609038 | 0.93 | CYP19A1 (0.47) | CYP19A1ALDH1A1KDM4EUSP2MAPT | |
| SCHEMBL29064176 | 0.78 | MAPT (0.50) | CYP19A1ALDH1A1KDM4EUSP2MAPT | |
| SCHEMBL5883440 | 0.78 | ALDH1A1 (0.55) | CYP19A1ALDH1A1KDM4EUSP2MAPT | |
| SCHEMBL14218923 | 0.74 | MAPT (0.54) | ALDH1A1KDM4EUSP2MAPTGAA | |
| SCHEMBL1272528 | 0.74 | ALDH1A1 (0.39) | CYP19A1ALDH1A1KDM4EUSP2MAPT | |
| SCHEMBL26185782 | 0.72 | TRPA1 (0.58) | CYP19A1ALDH1A1MAPTTSHRTRPA1 | |
| SCHEMBL4211349 | 0.72 | ACHE (0.56) | ALDH1A1KDM4EUSP2MAPTGAA | |
| SCHEMBL1792533 | 0.72 | CYP1A1 (0.61) | CYP19A1ALDH1A1MAPTCA1CA2 | |
| SCHEMBL16824962 | 0.71 | MAPT (0.47) | CYP19A1ALDH1A1KDM4EUSP2MAPT | |
| SCHEMBL3951418 | 0.71 | GABRA1 (0.56) | ALDH1A1KDM4EUSP2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376656-B1 | DISAZO DYES, TRIAZINE DYES | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2002-04-23 | — | — | US | disclosed |
| US-6025478-A | HIGH REACTIVITY AND FIXING CAPACITY, GOOD LOW TEMPERATURE DYEING, GOOD COLOR INTENSITY, LIGHTFASTNESS, WASHFASTNESS | BAYER AG (DE) | 2000-02-15 | — | — | US | disclosed |
| US-5502174-A | Reactive dyestuffs based on a substituted barbituric acid | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| US-5319074-A | Colorfast dyes for cellulose and polyamides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-06-07 | — | — | US | disclosed |
| US-5278293-A | Aromatic amide-alkylenesulfonic acid fiber-reactive dyes | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-11 | — | — | US | disclosed |
| US-5274083-A | A 2-halopyrimidinylaminoalkylamino-4-chloro-6-sulfonyl-substituted chromophore group-s-triazine | BAYER AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |
| US-4839469-A | WET- AND LIGHT-FAST BLUE DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-13 | — | — | US | disclosed |
| US-4649193-A | COTTON, WOOL, POLYAMIDES; COLOR-AND WASH FASTNESS | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-10 | — | — | US | disclosed |