Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717755 | 1.00 | MEN1 (0.41) | MEN1KMT2ATDP1L3MBTL1NOS2 | |
| SCHEMBL7717293 | 0.90 | LMNA (0.39) | MEN1KMT2ANOS2NOS3CYP2D6 | |
| SCHEMBL7717290 | 0.90 | LMNA (0.39) | MEN1KMT2ANOS2NOS3CYP2D6 | |
| SCHEMBL18938347 | 0.78 | KMT2A (0.61) | MEN1KMT2ATDP1L3MBTL1GRIN1 | |
| SCHEMBL22044257 | 0.71 | CYP2D6 (0.66) | MEN1KMT2ATDP1L3MBTL1GRIN1 | |
| SCHEMBL29506425 | 0.70 | L3MBTL1 (0.41) | TDP1L3MBTL1NOS2POLBALDH1A1 | |
| SCHEMBL20017352 | 0.69 | MEN1 (0.50) | MEN1KMT2ATDP1L3MBTL1GRIN1 | |
| SCHEMBL5013786 | 0.68 | TDP1 (0.54) | MEN1KMT2ATDP1L3MBTL1POLB | |
| SCHEMBL24022828 | 0.67 | NPC1 (0.61) | MEN1KMT2AGRIN1GRIN2BPOLB | |
| SCHEMBL22044441 | 0.67 | PARP1 (0.55) | TDP1L3MBTL1POLBHTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6379655-B1 | FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION | SOCIETE L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | claimed |
| US-6379655-B1 | FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION | SOCIETE L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | disclosed |