Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL947586 | 0.88 | SLC6A2 (0.35) | SLC6A2SLC6A4OPRD1 | |
| SCHEMBL7662942 | 0.74 | — | — | |
| SCHEMBL7713683 | 0.74 | — | — | |
| SCHEMBL9660602 | 0.73 | SIGMAR1 (0.36) | SLC6A2SLC6A4OPRD1 | |
| SCHEMBL678404 | 0.73 | SLC6A2 (0.30) | SLC6A2SLC6A4 | |
| SCHEMBL3301449 | 0.73 | KDM4E (0.31) | SLC6A2SLC6A4OPRD1 | |
| SCHEMBL7427732 | 0.71 | FDPS (0.32) | — | |
| SCHEMBL14700537 | 0.71 | — | — | |
| SCHEMBL9661910 | 0.70 | SIGMAR1 (0.43) | SLC6A2SLC6A4OPRD1 | |
| SCHEMBL23668190 | 0.69 | HTR1A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002087587-A2 | 4-AMINOSULFONYLQUINAZOLINES AND -QUINOLINES AS TYROSINE KINASE INHIBITORS | CELLTECH R & D LIMITED (GB) | 2002-11-07 | — | — | WO | disclosed |