Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 10/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426333 | 0.89 | LMNA (0.48) | LMNAGRM2PIM1PIM3PIM2 | |
| SCHEMBL3112850 | 0.89 | LMNA (0.48) | LMNAGRM2PIM1PIM3PIM2 | |
| Hydrochloric Acid SCHEMBL17048486 | 0.87 | LMNA (0.47) | LMNAGRM2PIM1PIM3PIM2 | |
| SCHEMBL6027026 | 0.87 | NOS2 (0.50) | LMNAGRM2 | |
| SCHEMBL31507558 | 0.85 | LMNA (0.55) | LMNAGRM2PIM1PIM3PIM2 | |
| SCHEMBL26684911 | 0.85 | LMNA (0.55) | LMNAGRM2PIM1PIM3PIM2 | |
| SCHEMBL17382065 | 0.82 | POLB (0.51) | LMNAGRM2POLBNQO2NNMT | |
| SCHEMBL11620076 | 0.79 | LMNA (0.40) | LMNAGRM2HTT | |
| SCHEMBL9636253 | 0.77 | LMNA (0.56) | LMNAGRM2PIM1PIM3PIM2 | |
| SCHEMBL5370102 | 0.77 | SMN1; SMN2 (0.46) | LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150218192-A1 | Polysilylated Organosilane Compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2015-08-06 | — | — | US | disclosed |
| EP-0728744-B1 | Process for the preparation of carboxylic acids of nitrogen-containing heterocycles | LONZA AG (CH) | 2002-04-10 | — | — | EP | disclosed |
| EP-0627422-B1 | Process for the preparation of carboxamides of nitrogen-containing aromatic heterocycles | LONZA AG (CH) | 1997-04-09 | — | — | EP | disclosed |
| US-5614636-A | Process for the preparation of 2,4-pyridine dicarboxylic acid | LONZA LTD. (CH) | 1997-03-25 | — | — | US | disclosed |
| EP-0728744-A2 | Process for the preparation of carboxylic acids of nitrogen-containing heterocycles | LONZA A.G. (CH) | 1996-08-28 | — | — | EP | disclosed |
| EP-0627422-A2 | Process for the preparation of carboxamides of nitrogen-containing aromatic heterocycles, as well as their use | LONZA A.G. (CH) | 1994-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150218192-A1 | Polysilylated Organosilane Compounds | ALG8, UGT1A9, SI | LMNA 3846/4885GRM2 2797/4885PIM1 2350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.