Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 1/20 | 0.49 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 12/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956416 | 0.90 | BDKRB2 (0.50) | BDKRB2BDKRB1RORCHCRTR1HCRTR2 | |
| SCHEMBL8187379 | 0.89 | BDKRB2 (0.43) | BDKRB2BDKRB1HCRTR1HCRTR2CASP3 | |
| SCHEMBL6939720 | 0.86 | MMP8 (0.53) | BDKRB2BDKRB1RORC | |
| SCHEMBL6944021 | 0.86 | MMP8 (0.53) | BDKRB2BDKRB1RORC | |
| SCHEMBL7811395 | 0.85 | BDKRB2 (0.60) | BDKRB2BDKRB1RORCHCRTR1HCRTR2 | |
| SCHEMBL7954323 | 0.84 | TSHR (0.43) | BDKRB2BDKRB1 | |
| SCHEMBL7649083 | 0.83 | ALDH1A1 (0.54) | BDKRB2BDKRB1RORC | |
| SCHEMBL6936920 | 0.81 | RORC (0.54) | RORCCASP3 | |
| SCHEMBL6936917 | 0.81 | RORC (0.54) | RORCCASP3 | |
| SCHEMBL7643692 | 0.81 | RORC (0.45) | BDKRB2BDKRB1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384222-B1 | BRADYKININ HORMONE ANTAGONIST; ANALGESIC, ANTIINFLAMMATORY; ASTHMA, CEREBRAL TRAUMATIC SHOCK AND ALLERGIC RHINITIS; ETHERIFICATION, AMIDATION | FOURNIER INDUSTRIE ET SANTE (FR) | 2002-05-07 | — | — | US | disclosed |
| US-6211181-B1 | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIALLERGENS, AND ANTIASTHMATICS | FOURNIER INDUSTRIE ET SANTE (FR) | 2001-04-03 | — | — | US | disclosed |
| US-6080758-A | ANALGESICS, ANTIINFLAMMATORY AGENTS; ASTHMA; ALLERGIC RHINITIS | FOURNIER INDUSTRIE ET SANTE (FR) | 2000-06-27 | — | — | US | disclosed |
| US-6063791-A | N-benzenesulfonyl-L-proline derivatives, method for preparing and therapeutic use | FOURNIER INDUSTRIE ET SANTE (FR) | 2000-05-16 | — | — | US | disclosed |