Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.43 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 2/20 | 0.40 |
| ▸ | SKP1 | P63208 | 2/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716782 | 0.86 | DRD2 (0.69) | DRD2ADRA1A | |
| SCHEMBL7716756 | 0.82 | DRD2 (0.51) | DRD2CKS1BSKP1SKP2 | |
| SCHEMBL7714964 | 0.81 | ADRA1A (0.44) | DRD2ADRA1DADRA1AADRA1BSSTR4 | |
| SCHEMBL7714962 | 0.80 | ADRA1A (0.47) | DRD2ADRA1DADRA1AADRA1BSSTR4 | |
| SCHEMBL7711060 | 0.79 | DRD2 (0.51) | DRD2CKS1BSKP1SKP2 | |
| SCHEMBL7711219 | 0.79 | DRD2 (0.48) | DRD2CKS1BSKP1SKP2 | |
| SCHEMBL7711275 | 0.78 | NPY1R (0.54) | DRD2 | |
| SCHEMBL8221705 | 0.76 | CKS1B (0.48) | DRD2ADRA1DADRA1AADRA1BCKS1B | |
| SCHEMBL7711061 | 0.74 | CHRM4 (0.48) | — | |
| SCHEMBL7714679 | 0.74 | CHRM4 (0.49) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376503-B1 | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC | 2002-04-23 | — | — | US | disclosed |