Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PTGIR | P43119 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7720159 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTEPHX1PKMPOLB | |
| SCHEMBL7720991 | 0.86 | PKM (0.37) | ALDH1A1MAPTEPHX1PKMPOLB | |
| SCHEMBL4511136 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPTEPHX1POLBL3MBTL1 | |
| SCHEMBL4511130 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPTEPHX1POLBL3MBTL1 | |
| SCHEMBL7720138 | 0.74 | PKM (0.36) | ALDH1A1MAPTEPHX1PKMPOLB | |
| SCHEMBL5316917 | 0.73 | PKM (0.46) | ALDH1A1PKMKMT2APTGIRSMN1; SMN2 | |
| SCHEMBL5316920 | 0.73 | PKM (0.46) | ALDH1A1PKMKMT2APTGIRSMN1; SMN2 | |
| SCHEMBL7721348 | 0.72 | PKM (0.39) | EPHX1PKMKMT2APTGIRHDAC1 | |
| SCHEMBL7721339 | 0.70 | PKM (0.39) | EPHX1PKMKMT2APTGIRHDAC1 | |
| SCHEMBL23322556 | 0.64 | PTGIR (0.65) | EPHX1PTGIRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387949-B1 | ANALGESICS | ASTRAZENECA CANADA INC. (CA) | 2002-05-14 | — | — | US | disclosed |