Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | GPR39 | O43194 | 1/20 | 0.34 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721348 | 0.77 | PKM (0.39) | PKMKMT2AKDM4CHDAC1HDAC6 | |
| SCHEMBL5316920 | 0.76 | PKM (0.46) | PKMMEN1KMT2AOPRM1HDAC1 | |
| SCHEMBL5316917 | 0.76 | PKM (0.46) | PKMMEN1KMT2AOPRM1HDAC1 | |
| SCHEMBL7720138 | 0.73 | PKM (0.36) | PKMMEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL7720991 | 0.70 | PKM (0.37) | PKMMEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL7720162 | 0.70 | ALDH1A1 (0.40) | PKMKMT2AHDAC1HDAC6EPHX1 | |
| SCHEMBL7720159 | 0.70 | ALDH1A1 (0.40) | PKMKMT2AHDAC1HDAC6EPHX1 | |
| SCHEMBL14493867 | 0.64 | PKM (0.41) | PKMMEN1KMT2AOPRM1HDAC1 | |
| Hydrochloric Acid SCHEMBL5395243 | 0.63 | IRAK4 (0.44) | KDM1AMAOA | |
| SCHEMBL17700175 | 0.62 | GPR39 (0.56) | MEN1KMT2AGPR39 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387949-B1 | ANALGESICS | ASTRAZENECA CANADA INC. (CA) | 2002-05-14 | — | — | US | disclosed |