Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | VCP | P55072 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721348 | 0.75 | PKM (0.39) | PKMKMT2AHDAC1HDAC6KDM1A | |
| SCHEMBL7720991 | 0.75 | PKM (0.37) | PKMKMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL7720162 | 0.74 | ALDH1A1 (0.40) | PKMKMT2AMAPTALDH1A1POLB | |
| SCHEMBL7720159 | 0.74 | ALDH1A1 (0.40) | PKMKMT2AMAPTALDH1A1POLB | |
| SCHEMBL7721339 | 0.73 | PKM (0.39) | PKMKMT2AMEN1HDAC1HDAC6 | |
| SCHEMBL5316917 | 0.73 | PKM (0.46) | PKMKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL5316920 | 0.73 | PKM (0.46) | PKMKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL3972652 | 0.66 | MAPT (0.51) | KMT2AMAPTMAPK1ALDH1A1MEN1 | |
| SCHEMBL3972651 | 0.66 | MAPT (0.51) | KMT2AMAPTMAPK1ALDH1A1MEN1 | |
| SCHEMBL23997424 | 0.63 | ALDH1A1 (0.51) | PKMKMT2AMAPTMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387949-B1 | ANALGESICS | ASTRAZENECA CANADA INC. (CA) | 2002-05-14 | — | — | US | disclosed |