Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721339 | 0.77 | PKM (0.39) | PKMHDAC1HDAC6KDM1ARCOR1 | |
| SCHEMBL5316917 | 0.76 | PKM (0.46) | PKMHDAC1HDAC6PTGIRAGTR2 | |
| SCHEMBL5316920 | 0.76 | PKM (0.46) | PKMHDAC1HDAC6PTGIRAGTR2 | |
| SCHEMBL7720138 | 0.75 | PKM (0.36) | PKMHDAC1HDAC6KDM1ARCOR1 | |
| SCHEMBL7720991 | 0.72 | PKM (0.37) | PKMHDAC1HDAC6KDM1ARCOR1 | |
| SCHEMBL7720159 | 0.72 | ALDH1A1 (0.40) | PKMHDAC1HDAC6EPHX1PTGIR | |
| SCHEMBL7720162 | 0.72 | ALDH1A1 (0.40) | PKMHDAC1HDAC6EPHX1PTGIR | |
| SCHEMBL14493867 | 0.64 | PKM (0.41) | PKMHDAC1HDAC6PTGIRAGTR2 | |
| SCHEMBL4067618 | 0.62 | PKM (0.51) | PKMEPHX1AGTR2NPY5RKMT2A | |
| SCHEMBL11282486 | 0.61 | ATM (0.56) | PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387949-B1 | ANALGESICS | ASTRAZENECA CANADA INC. (CA) | 2002-05-14 | — | — | US | disclosed |