SCHEMBL7721282

SCHEMBL7721282

CC(C)NC(=O)CCCN(C)C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.57
FAAH O00519 1/20 0.57
MAPK1 P28482 1/20 0.57
KMT2A Q03164 1/20 0.57
DNM1 Q05193 2/20 0.44
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
PAOX Q6QHF9 1/20 0.39
HPGD P15428 3/20 0.39
NLRP1 Q9C000 1/20 0.39
KDM4A O75164 5/20 0.38
KDM4C Q9H3R0 5/20 0.38
KDM5A P29375 1/20 0.38
KDM7A Q6ZMT4 1/20 0.38
PHF8 Q9UPP1 1/20 0.38
KDM2A Q9Y2K7 1/20 0.38
CHRM5 P08912 1/20 0.38
CHRM3 P20309 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23175882 0.92 MEN1 (0.63) MEN1FAAHMAPK1KMT2ADNM1
SCHEMBL7132152 0.87 MEN1 (0.50) MEN1FAAHMAPK1KMT2ADNM1
SCHEMBL15147831 0.84 DNM1 (0.42) MEN1FAAHMAPK1KMT2ADNM1
SCHEMBL24477430 0.84 FAAH (0.53) MEN1FAAHMAPK1KMT2ADNM1
SCHEMBL13241299 0.82 MEN1 (0.43) MEN1FAAHMAPK1KMT2ADNM1
SCHEMBL12934925 0.82 FAAH (0.78) MEN1FAAHMAPK1KMT2ADNM1
SCHEMBL5909190 0.82 FAAH (0.71) MEN1FAAHMAPK1KMT2ADNM1
SCHEMBL23420467 0.81 FAAH (0.50) MEN1FAAHMAPK1KMT2ADNM1
SCHEMBL12934924 0.80 FAAH (0.83) MEN1FAAHMAPK1KMT2ADNM1
SCHEMBL12934930 0.80 FAAH (0.83) MEN1FAAHMAPK1KMT2ADNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4241767-A2 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS Arbutus Biopharma Corporation (CA) 2023-09-13 EP disclosed
US-11351265-B2 Process for formulating an anionic agent DICERNA PHARMACEUTICALS, INC. (US) 2022-06-07 US disclosed
US-20210292303-A1 AMINE CATIONIC LIPIDS AND USES THEREOF DICERNA PHARMACEUTICALS, INC. 2021-09-23 US disclosed
US-20190151461-A1 PROCESS FOR FORMULATING AN ANIONIC AGENT DICERNA PHARMACEUTICALS, INC. (US) 2019-05-23 US disclosed
US-20170137409-A1 Amine Cationic Lipids and Uses Thereof NOVO NORDISK A/S (DK) 2017-05-18 US disclosed
US-20170137409-A1 Amine Cationic Lipids and Uses Thereof NOVO NORDISK A/S (DK) 2017-05-18 US disclosed
US-9561228-B2 ERK inhibitors and uses thereof CELGENE AVILOMICS RESEARCH, INC. (US) 2017-02-07 US disclosed
US-9549983-B2 Amine cationic lipids and uses thereof DICERNA PHARMACEUTICALS, INC. (US) 2017-01-24 US disclosed
US-20150374842-A1 PROCESS FOR FORMULATING AN ANIONIC AGENT NOVO NORDISK A/S (DK) 2015-12-31 US disclosed
US-20140371293-A1 Amine Cationic Lipids and Uses Thereof DICERNA PHARMACEUTICALS, INC. (US) 2014-12-18 US disclosed
US-8198458-B2 Non-nucleoside reverse transcriptase inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-06-12 US disclosed
US-6875765-B2 Arylsulfonamide ethers, and methods of use thereof WARNER-LAMBERT COMPANY (US) 2005-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11351265-B2 Process for formulating an anionic agent PHOSPHO1, POLRMT, LIPA MEN1 1690/4885FAAH 1051/4885MAPK1 3823/4885
US-20190151461-A1 PROCESS FOR FORMULATING AN ANIONIC AGENT PHOSPHO1, POLRMT, LIPA MEN1 1690/4885FAAH 1051/4885MAPK1 3823/4885
US-20150374842-A1 PROCESS FOR FORMULATING AN ANIONIC AGENT PHOSPHO1, POLRMT, LIPA MEN1 1690/4885FAAH 1051/4885MAPK1 3823/4885
US-20140371293-A1 Amine Cationic Lipids and Uses Thereof SGMS2, SLC43A1, SGMS1 MEN1 1518/4885FAAH 1399/4885MAPK1 4590/4885
US-20170137409-A1 Amine Cationic Lipids and Uses Thereof SGMS2, SLC43A1, SGMS1 MEN1 1518/4885FAAH 1399/4885MAPK1 4590/4885
US-20210292303-A1 AMINE CATIONIC LIPIDS AND USES THEREOF SGMS2, SLC43A1, SGMS1 MEN1 1518/4885FAAH 1399/4885MAPK1 4590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.