Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721781 | 0.89 | ELANE (0.40) | MAPTPOLBPKMHSD17B10GLA | |
| SCHEMBL7721693 | 0.87 | KMT2A (0.39) | MAPTPOLBESR1LMNAKDM4E | |
| SCHEMBL3175601 | 0.86 | MMP1 (0.45) | POLBPKMCHRM2CHRM1KDM4E | |
| SCHEMBL7724564 | 0.85 | MAPT (0.56) | MAPTPOLBPKMPTGS2LMNA | |
| SCHEMBL3169804 | 0.84 | MMP13 (0.46) | POLBPKMKDM4EKMT2AALDH1A1 | |
| SCHEMBL384384 | 0.84 | MAPT (0.61) | MAPTPOLBPKMPTGS2LMNA | |
| SCHEMBL7695999 | 0.84 | ENPP3 (0.45) | LMNAALDH1A1GLAMMP1MMP9 | |
| SCHEMBL7697001 | 0.81 | ENPP3 (0.47) | POLBLMNAKMT2AALDH1A1GLA | |
| SCHEMBL563060 | 0.81 | ALDH1A1 (0.44) | MAPTPOLBADORA3LMNAKDM4E | |
| SCHEMBL3166504 | 0.80 | MMP9 (0.45) | POLBPTGS2KDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |