Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721805 | 0.89 | ELANE (0.53) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL7717485 | 0.87 | KMT2A (0.43) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL7721776 | 0.87 | KMT2A (0.43) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL7722379 | 0.87 | KMT2A (0.43) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL7722385 | 0.86 | LMNA (0.51) | KMT2AELANEMAPTALDH1A1CYP1A2 | |
| SCHEMBL9010795 | 0.84 | CES2 (0.48) | KMT2ARECQLMAPTALDH1A1LMNA | |
| SCHEMBL7697516 | 0.84 | MMP2 (0.42) | KMT2AMAPTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7724562 | 0.84 | KMT2A (0.51) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL9010786 | 0.84 | ALDH1A1 (0.52) | KMT2ASMN1; SMN2MAPTALDH1A1CYP1A2 | |
| SCHEMBL7724582 | 0.83 | ELANE (0.47) | KMT2AELANEMAPTALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |